ArticleJournal of clinical medicine2022
Which Actigraphy Dimensions Predict Longitudinal Outcomes in Bipolar Disorders?
Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed.
- Longer Sleep Duration Predicts Progression to Bipolar or Psychotic Disorders in Youth Accessing Early Intervention Mental Health Services.Bipolar disorders · 2026Article
- Melatonin Circadian Phase Timing and Stability: Associations With Mood Symptoms Among a Clinically-Enriched Sample of Young Adults With Mood Disorders.Journal of pineal research · 2026Article
- Circadian rhythm parameters differentiate euthymic, manic and depressive mood states in bipolar disorders - an explorative pilot study.International journal of bipolar disorders · 2025Article
- Sleep disturbance as a marker of postpartum psychosis risk: a prospective actigraphy study.BMC psychiatry · 2025Observational
- Polygenic risk scores for mood disorders and actigraphy estimates of sleep and circadian rhythms: A preliminary study in bipolar disorders.Journal of sleep research · 2025Article
- Sleep Disturbances in the Prodromal Phase of Mood Episodes in Patients with Bipolar Disorder: A Replicated Single-case Design.Journal for person-oriented research · 2025Article
- Forecasting the course of bipolar disorder using rest-activity rhythms: Protocol for a multi-study modelling project.Wellcome open research · 2025Article
- Sleep and psychiatric disorders: Bidirectional interactions and shared neurobiological mechanisms.PLOS mental health · 2025Review
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
Bipolar disorder (BD) is characterized by recurrent mood episodes. It is increasingly suggested that disturbances in sleep-wake cycles and/or circadian rhythms could represent valuable predictors of recurrence, but few studies have addressed this question. Euthymic individuals with BD (n = 69) undertook 3 weeks of actigraphy recording and were then followed up for a median duration of 3.5 years. Principal component analyses were used to identify core dimensions of sleep quantity/variability and circadian rhythmicity. Associations between clinical variables and actigraphy dimensions and time to first recurrence were explored using survival analyses, and then using area under the curve (AUC) analyses (early vs. late recurrence). Most participants (64%) experienced a recurrence during follow-up (median survival time: 18 months). After adjusting for potential confounding factors, an actigraphy dimension comprising amplitude and variability/stability of circadian rhythms was a significant predictor of time to recurrence (
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