ArticleJournal of clinical medicine2022
External Validation of the Hospital Frailty-Risk Score in Predicting Clinical Outcomes in Older Heart-Failure Patients in Australia.
Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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The trial behind it
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.
- Systematic Review of the Association of the Hospital Frailty Risk Score with Mortality in Patients with Cerebrovascular and Cardiovascular Disease.Current cardiology reviews · 2024Pooled it
- Relative Effectiveness of High-Dose Versus Standard-Dose Influenza Vaccination Against Hospitalizations and Deaths According to Frailty Score: A Post Hoc Analysis of the DANFLU-1 Randomized Trial.The Journal of infectious diseases · 2026Trial
- Article
- Association between hospital frailty risk score, risk of sepsis and adverse outcomes across all adult ages.PloS one · 2026Article
- Comparison of two electronic medical record-based frailty assessment tools and their association with adverse outcomes in older hospitalized patients with urgent admissions.International journal of emergency medicine · 2025Article
- Guideline-Concordant Antibiotic Treatment for Hospitalised Patients with Community-Acquired Pneumonia and Clinical Outcomes at a Tertiary Hospital in Australia.Antibiotics (Basel, Switzerland) · 2025Article
- Clinical Instability at Discharge and Post-Discharge Outcomes in Patients with Community-Acquired Pneumonia: An Observational Study.Journal of clinical medicine · 2025Article
- Metformin reduces the risk of frailty: evidence from a Mendelian randomization study.Diabetology & metabolic syndrome · 2025Article
- Kidney status and events preceding death in heart failure: A real-world nationwide study.European journal of heart failure · 2025Article
- The Hospital Frailty Risk Score as a Predictor of Mortality, Complications, and Resource Utilization in Heart Failure: Implications for Managing Critically Ill Patients.Biomedicines · 2025Article
- Using the Hospital Frailty Risk Score to predict length of stay across all adult ages.PloS one · 2025Article
- Prognostic Value of Frailty in Patients With Takotsubo Cardiomyopathy.Clinical cardiology · 2025Article
- Age does not improve the predictive ability of the Hospital Frailty Risk Score for length of stay.PloS one · 2025Article
- Comparing Outcomes of Community-Acquired Pneumonia Patients Discharged from General Medicine and Respiratory Units in Australia: A Propensity Score-Matched Analysis.Journal of clinical medicine · 2024Article
- Proof-of-concept for an automatable mortality prediction scoring in hospitalised older adults.Frontiers in medicine · 2024Article
- Hip fracture incidence and post-fracture mortality in Victoria, Australia: a state-wide cohort study.Archives of osteoporosis · 2023Article
- Frailty is a predictor for worse outcomes in patients hospitalized withAnnals of gastroenterologyArticle
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
Abstract
Frailty is common in older hospitalised heart-failure (HF) patients but is not routinely assessed. The hospital frailty-risk score (HFRS) can be generated from administrative data, but it needs validation in Australian health-care settings. This study determined the HFRS scores at presentation to hospital in 5735 HF patients ≥ 75 years old, admitted over a period of 7 years, at two tertiary hospitals in Australia. Patients were classified into 3 frailty categories: HFRS < 5 (low risk), 5−15 (intermediate risk) and >15 (high risk). Multilevel multivariable regression analysis determined whether the HFRS predicts the following clinical outcomes: 30-day mortality, length of hospital stay (LOS) > 7 days, and 30-day readmissions; this was determined after adjustment for age, sex, Charlson index and socioeconomic status. The mean (SD) age was 76.1 (14.0) years, and 51.9% were female. When compared to the low-risk HFRS group, patients in the high-risk HFRS group had an increased risk of 30-day mortality and prolonged LOS (adjusted OR (aOR) 2.09; 95% CI 1.21−3.60) for 30-day mortality, and an aOR of 1.56 (95% CI 1.01−2.43) for prolonged LOS (c-statistics 0.730 and 0.682, respectively). Similarly, the 30-day readmission rate was significantly higher in the high-risk HFRS group when compared to the low-risk group (aOR 1.69; 95% CI 1.06−2.69; c-statistic = 0.643). The HFRS, derived at admission, can be used to predict ensuing clinical outcomes among older hospitalised HF patients.
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