Evidence map›Paper›PMID 35456275›Full record

ArticleJournal of clinical medicine2022

Necrotizing Fasciitis of the Upper Limb: Optimizing Management to Reduce Complications.

Simone La Padula, Rosita Pensato, Antonio Zaffiro, Oana Hermeziu, Francesco D'Andrea, Chiara Pizza, Jean Paul Meningaud, Barbara Hersant

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
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  3. A Case of Necrotizing Fasciitis That Rapidly Progressed after a Minor Injury.Journal of plastic and reconstructive surgery · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Simone La PadulaDepartment of Plastic and Reconstructive Surgery, Università Degli Studi di Napoli Federico II, Via Pansini 5, 80131 Naples, Italy.ORCID 0000-0003-3543-9024
Rosita PensatoDepartment of Plastic and Reconstructive Surgery, Università Degli Studi di Napoli Federico II, Via Pansini 5, 80131 Naples, Italy.
Antonio ZaffiroDepartment of Plastic and Reconstructive Surgery, Università Degli Studi di Napoli Federico II, Via Pansini 5, 80131 Naples, Italy.
Oana HermeziuDepartment of Plastic, Reconstructive and Maxillo Facial Surgery, Henri Mondor Hospital, University Paris XII, 51 Avenue du Maréchal de Lattre de Tassigny, 94000 Creteil, France.
Francesco D'AndreaDepartment of Plastic and Reconstructive Surgery, Università Degli Studi di Napoli Federico II, Via Pansini 5, 80131 Naples, Italy.
Chiara PizzaDepartment of Plastic, Reconstructive and Maxillo Facial Surgery, Henri Mondor Hospital, University Paris XII, 51 Avenue du Maréchal de Lattre de Tassigny, 94000 Creteil, France.
Jean Paul MeningaudDepartment of Plastic, Reconstructive and Maxillo Facial Surgery, Henri Mondor Hospital, University Paris XII, 51 Avenue du Maréchal de Lattre de Tassigny, 94000 Creteil, France.
Barbara HersantDepartment of Plastic, Reconstructive and Maxillo Facial Surgery, Henri Mondor Hospital, University Paris XII, 51 Avenue du Maréchal de Lattre de Tassigny, 94000 Creteil, France.
Université Paris-Est Créteil · FRUniversity of Naples Federico II · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNecrotizing fasciitis (NF) is a severe, potentially life-threatening condition. The aim of this study is to identify strategies aimed at reducing complications in patients with NF of the upper limb.

methodsWe conducted a retrospective study on patients admitted to our Unit for suspected NF of the upper limb. The analyzed data included patient characteristics, delay before primary care, clinical and biological signs upon arrival, pathogens involved, and the rate of amputations and mortality.

resultsA total of 21 patients presented with confirmed necrotizing bacterial dermohypodermitis-NBDH with NF (NBDH-NF) affecting the upper limb. The mean delay between the onset of symptoms and the clinical examination in the Emergency Dermatology Unit was 48 h (range: 6 to 72 h). The mean delay between admission and primary surgery was 150 min (range: 60 min to 280 min). No amputations were performed. All patients were alive one year after the first surgical procedure.

conclusionsOur study demonstrated that it is possible to reduce mortality and morbidity rates in NF of the upper limb. Timely diagnosis and early treatment and a multidisciplinary medico-surgical dedicated team providing care can significantly modify the outcomes. Early surgical debridement is the most important factor affecting the prognosis of these infections.

Indexed as

hand infectionhand reconstructionnecrotizing fasciitissoft tissue infectionupper limb infectionupper limb necrotizing fasciitis

Identifiers

PMID35456275
PMCPMC9027995
OpenAlexW4223962689

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.