Evidence map›Paper›PMID 35456195›Full record

ArticleJournal of clinical medicine2022

Comparisons of Clinical Features and Outcomes of COVID-19 between Patients with Pediatric Onset Inflammatory Rheumatic Diseases and Healthy Children.

Fatih Haslak, Sevki Erdem Varol, Aybuke Gunalp, Ozge Kaynar, Mehmet Yildiz, Amra Adrovic, Sezgin Sahin, Gulsen Kes, Ayse Ayzit-Kilinc, Beste Akdeniz and 10 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Risk Factors for Pediatric Critical COVID-19: A Systematic Review and Meta-Analysis.Journal of the Pediatric Infectious Diseases Society · 2024
    Pooled it
  2. Article
  3. Observational
  4. Risk Factors for Pediatric Critical COVID-19: A Systematic Review and Meta-Analysis.medRxiv : the preprint server for health sciences · 2024
    Article
  5. Article
  6. Article
  7. Article
  8. COVID-19 and Inborn Errors of Immunity.Physiology (Bethesda, Md.) · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 1 institution in 1 country.

Fatih HaslakDepartment of Pediatric Rheumatology, Cerrahpasa Medical School, Istanbul University-Cerrahpasa, Istanbul 34303, Turkey.
Sevki Erdem VarolDepartment of Pediatric Rheumatology, Cerrahpasa Medical School, Istanbul University-Cerrahpasa, Istanbul 34303, Turkey.
Aybuke GunalpDepartment of Pediatric Rheumatology, Cerrahpasa Medical School, Istanbul University-Cerrahpasa, Istanbul 34303, Turkey.
Ozge KaynarDepartment of Pediatric Rheumatology, Cerrahpasa Medical School, Istanbul University-Cerrahpasa, Istanbul 34303, Turkey.
Mehmet YildizDepartment of Pediatric Rheumatology, Cerrahpasa Medical School, Istanbul University-Cerrahpasa, Istanbul 34303, Turkey.
Amra AdrovicDepartment of Pediatric Rheumatology, Cerrahpasa Medical School, Istanbul University-Cerrahpasa, Istanbul 34303, Turkey.
Sezgin SahinDepartment of Pediatric Rheumatology, Cerrahpasa Medical School, Istanbul University-Cerrahpasa, Istanbul 34303, Turkey.ORCID 0000-0002-5365-3457
Gulsen KesDepartment of Pediatric Infectious Diseases, Cerrahpasa Medical School, Istanbul University-Cerrahpasa, Istanbul 34303, Turkey.
Ayse Ayzit-KilincDepartment of Pediatric Pulmonology, Cerrahpasa Medical School, Istanbul University-Cerrahpasa, Istanbul 34303, Turkey.
Beste AkdenizDepartment of Pediatric Infectious Diseases, Cerrahpasa Medical School, Istanbul University-Cerrahpasa, Istanbul 34303, Turkey.
Pinar OnalDepartment of Pediatric Infectious Diseases, Cerrahpasa Medical School, Istanbul University-Cerrahpasa, Istanbul 34303, Turkey.
Gozde ApaydinDepartment of Pediatric Infectious Diseases, Cerrahpasa Medical School, Istanbul University-Cerrahpasa, Istanbul 34303, Turkey.ORCID 0000-0003-2433-1827
Deniz AygunDepartment of Pediatric Infectious Diseases, Cerrahpasa Medical School, Istanbul University-Cerrahpasa, Istanbul 34303, Turkey.ORCID 0000-0002-7830-7155
Huseyin ArslanDepartment of Pediatric Pulmonology, Cerrahpasa Medical School, Istanbul University-Cerrahpasa, Istanbul 34303, Turkey.
Azer Kilic-BaskanDepartment of Pediatric Pulmonology, Cerrahpasa Medical School, Istanbul University-Cerrahpasa, Istanbul 34303, Turkey.ORCID 0000-0002-7600-7909
Evrim HepkayaDepartment of Pediatric Pulmonology, Cerrahpasa Medical School, Istanbul University-Cerrahpasa, Istanbul 34303, Turkey.
Ozge MeralDepartment of Pediatric Pulmonology, Cerrahpasa Medical School, Istanbul University-Cerrahpasa, Istanbul 34303, Turkey.
Kenan BarutDepartment of Pediatric Rheumatology, Cerrahpasa Medical School, Istanbul University-Cerrahpasa, Istanbul 34303, Turkey.
Haluk Cezmi CokugrasDepartment of Pediatric Infectious Diseases, Cerrahpasa Medical School, Istanbul University-Cerrahpasa, Istanbul 34303, Turkey.
Ozgur KasapcopurDepartment of Pediatric Rheumatology, Cerrahpasa Medical School, Istanbul University-Cerrahpasa, Istanbul 34303, Turkey.ORCID 0000-0002-1125-7720
Istanbul University-Cerrahpaşa · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(1) Background: We aimed to describe the clinical features and outcomes of coronavirus disease-2019 (COVID-19) in children and late adolescents with inflammatory rheumatic diseases (IRD) and to measure their severity risks by comparing them with healthy children. (2) Methods: Among children and late adolescents found to be severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) positive via polymerase chain reaction (PCR) test, IRD patients with an at least six-months follow-up duration, and healthy children were included in the study. Data were obtained retrospectively. (3) Results: A total of 658 (339 (51.5%) females) (healthy children: 506, IRD patients: 152) subjects were included in the study. While 570 of 658 (86.6%) experienced COVID-19-related symptoms, only 21 (3.19%) required hospitalization with a median duration of 5 (1-30) days. Fever, dry cough, and fatigue were the most common symptoms. None of evaluated subjects died, and all recovered without any significant sequelae. The presence of any IRD was found to increase the risk of both hospitalization (OR: 5.205; 95% CI: 2.003-13.524) and symptomatic infection (OR: 2.579; 95% CI: 1.068-6.228). Furthermore, increasing age was significantly associated with symptomatic infection (OR: 1.051; 95% CI: 1.009-1.095). (4) Conclusions: Our study emphasizes that pediatric rheumatologists should monitor their patients closely for relatively poor COVID-19 outcomes.

Indexed as

COVID-19familial Mediterranean feverpediatricsrheumatologySARS-CoV-2

Identifiers

PMID35456195
PMCPMC9030434
OpenAlexW4223547556

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.