Evidence map›Paper›PMID 35456149›Full record

ArticlePathogens (Basel, Switzerland)2022

Group B

Eric R Espinal, Teralan Matthews, Brianna M Holder, Olivia B Bee, Gabrielle M Humber, Caroline E Brook, Mustafa Divyapicigil, Jerod Sharp, Brandon J Kim

Open access · goldAbstract read
In one paragraph

Article in Pathogens (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 24 citations in OpenAlex.

  1. A cross-strain CRISPRi sgRNA library forMicrobiology resource announcements · 2026
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  3. CRISPR interference in aJournal of bacteriology · 2026
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  9. Microbiology resource announcements · 2024
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  15. Article
  16. Pathogenic bacteria exploit transferrin receptor transcytosis to penetrate the blood-brain barrier.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  17. Review
  18. Article
  19. Platelets promote human macrophages-mediated macropinocytosis ofFrontiers in cellular and infection microbiology · 2023
    Article
  20. Macropinocytosis as a potential mechanism driving neurotropism ofFrontiers in cellular and infection microbiology · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Eric R EspinalDepartment of Biological Sciences, University of Alabama, 300 Hackberry Lane, Tuscaloosa, AL 35405, USA.
Teralan MatthewsDepartment of Biological Sciences, University of Alabama, 300 Hackberry Lane, Tuscaloosa, AL 35405, USA.
Brianna M HolderDepartment of Biological Sciences, University of Alabama, 300 Hackberry Lane, Tuscaloosa, AL 35405, USA.
Olivia B BeeDepartment of Chemical and Biological Engineering, University of Wisconsin, Madison, WI 53706, USA.
Gabrielle M HumberDepartment of Biological Sciences, University of Alabama, 300 Hackberry Lane, Tuscaloosa, AL 35405, USA.
Caroline E BrookDepartment of Biological Sciences, University of Alabama, 300 Hackberry Lane, Tuscaloosa, AL 35405, USA.
Mustafa DivyapicigilDepartment of Biological Sciences, University of Alabama, 300 Hackberry Lane, Tuscaloosa, AL 35405, USA.
Jerod SharpDepartment of Biological Sciences, University of Alabama, 300 Hackberry Lane, Tuscaloosa, AL 35405, USA.
Brandon J KimDepartment of Biological Sciences, University of Alabama, 300 Hackberry Lane, Tuscaloosa, AL 35405, USA.
University of Alabama · USUniversity of Wisconsin–Madison · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacterial meningitis is defined as serious inflammation of the central nervous system (CNS) in which bacteria infect the blood-brain barrier (BBB), a network of highly specialized brain endothelial cells (BECs). Dysfunction of the BBB is a hallmark of bacterial meningitis. Group B

Indexed as

bacterial meningitisblood–brain barriergroup B Streptococcushost–pathogen interactioniPSC-BECmacropinocytosis

Identifiers

PMID35456149
PMCPMC9028350
OpenAlexW4224302492

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.