Evidence map›Paper›PMID 35456132›Full record

ArticlePathogens (Basel, Switzerland)2022

Fecal DNA Virome Is Associated with the Development of Colorectal Neoplasia in a Murine Model of Colorectal Cancer.

Yingshi Li, Fan Zhang, Huimin Zheng, Sanjna Kalasabail, Chloe Hicks, Ka Yee Fung, Adele Preaudet, Tracy Putoczki, Julia Beretov, Ewan K A Millar and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pathogens (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Yingshi LiUNSW Microbiome Research Centre, St George and Sutherland Clinical Campuses, School of Clinical Medicine, UNSW Medicine and Health, The University of New South Wales, Sydney, NSW 2052, Australia.
Fan ZhangUNSW Microbiome Research Centre, St George and Sutherland Clinical Campuses, School of Clinical Medicine, UNSW Medicine and Health, The University of New South Wales, Sydney, NSW 2052, Australia.ORCID 0000-0001-8377-0235
Huimin ZhengUNSW Microbiome Research Centre, St George and Sutherland Clinical Campuses, School of Clinical Medicine, UNSW Medicine and Health, The University of New South Wales, Sydney, NSW 2052, Australia.
Sanjna KalasabailUNSW Microbiome Research Centre, St George and Sutherland Clinical Campuses, School of Clinical Medicine, UNSW Medicine and Health, The University of New South Wales, Sydney, NSW 2052, Australia.
Chloe HicksUNSW Microbiome Research Centre, St George and Sutherland Clinical Campuses, School of Clinical Medicine, UNSW Medicine and Health, The University of New South Wales, Sydney, NSW 2052, Australia.
Ka Yee FungPersonalised Oncology Division, The Walter and Eliza Hall Institute of Medical Research, Victoria, VIC 3052, Australia.
Adele PreaudetPersonalised Oncology Division, The Walter and Eliza Hall Institute of Medical Research, Victoria, VIC 3052, Australia.
Tracy PutoczkiPersonalised Oncology Division, The Walter and Eliza Hall Institute of Medical Research, Victoria, VIC 3052, Australia.ORCID 0000-0003-1639-4932
Julia BeretovSt George and Sutherland Clinical Campuses, School of Clinical Medicine, UNSW Medicine and Health, The University of New South Wales, Sydney, NSW 2052, Australia.
Ewan K A MillarSt George and Sutherland Clinical Campuses, School of Clinical Medicine, UNSW Medicine and Health, The University of New South Wales, Sydney, NSW 2052, Australia.ORCID 0000-0002-9778-3253
Emad El-OmarUNSW Microbiome Research Centre, St George and Sutherland Clinical Campuses, School of Clinical Medicine, UNSW Medicine and Health, The University of New South Wales, Sydney, NSW 2052, Australia.
Xiao-Tao JiangUNSW Microbiome Research Centre, St George and Sutherland Clinical Campuses, School of Clinical Medicine, UNSW Medicine and Health, The University of New South Wales, Sydney, NSW 2052, Australia.ORCID 0000-0003-1804-5314
Howard Chi Ho YimUNSW Microbiome Research Centre, St George and Sutherland Clinical Campuses, School of Clinical Medicine, UNSW Medicine and Health, The University of New South Wales, Sydney, NSW 2052, Australia.ORCID 0000-0002-2076-4361
UNSW Sydney · AUThe University of Melbourne · AUSutherland Hospital · AU

Funding

Australian Government N/A
6 · The paper itself

Abstract

Alteration of the gut virome has been associated with colorectal cancer (CRC); however, when and how the alteration takes place has not been studied. Here, we employ a longitudinal study in mice to characterize the gut virome alteration in azoxymethane (AOM)-induced colorectal neoplasia and identify important viruses associated with tumor growth. The number and size of the tumors increased as the mice aged in the AOM treated group, as compared to the control group. Tumors were first observed in the AOM group at week 12. We observed a significantly lower alpha diversity and shift in viral profile when tumors first appeared. In addition, we identified novel viruses from the genera

Indexed as

bacteriophagecolorectal neoplasiavirome

Identifiers

PMID35456132
PMCPMC9025118
OpenAlexW4223648946

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.