ReviewCells2022
Role of Estrogens in Menstrual Migraine.
Review in Cells, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06788977 (CEFALY Pregnancy Registry), which is not on this map. Cited by 54 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
CEFALY Pregnancy Registry
Who cites it
54 citing papers in PubMed, 102 citations in OpenAlex.
- The Estrogen-CGRP Axis in Migraine: Neuroimmune Mechanisms, Sex Differences, and Therapeutic Implications.Molecular neurobiology · 2026Review
- Stable angina in young women.European heart journal · 2026Review
- Clinical characteristics of pure menstrual migraine and menstrually-related migraine: a cross-sectional online questionnaire study.BMC neurology · 2026Article
- Exploratory metabolomic profiling in migraine with PFO reveals dysregulated pathways and highlights indoleacrylic acid.iScience · 2026Article
- Hip pain level variation in female femoroacetabular impingement syndrome patients in menstrual cycle.BMC musculoskeletal disorders · 2026Article
- Effectiveness of an Oral Supplementation of Phycocyanin and Palmitoylethanolamide for a Short-Term Prophylaxis of Menstrual Migraine: A Retrospective Observational Study.Biomedicines · 2026Article
- Hormonal Contraceptives and Migraine Frequency and Severity in Women: A Systematic Review and Meta-Analysis.Cureus · 2026Review
- Comparison of Substances in Combined Oral Contraceptives Used in Acne Vulgaris, Hirsutism, Migraine, and Dysmenorrhea.Medical science monitor : international medical journal of experimental and clinical research · 2026Review
- [Russian eligibility criteria for prescription of menopausal hormone therapy to patients with cardiovascular and metabolic diseases. Agreement document of RKO, ROAG, RAE, EAT, AFR, RNMOT, RAGG].Problemy endokrinologii · 2026Article
- Somatosensory cortical progesterone receptor signaling regulates the episodic to chronic migraine transformation.Neurobiology of disease · 2026Article
- Sex-dependent modulation of CGRPergic neurovascular activity by 5-CT in rats.Frontiers in pharmacology · 2026Article
- The special extract ERr 731Frontiers in pharmacology · 2026Article
- Paracetamol in pregnancy: Navigating clinical uncertainty and avoiding the communication pitfalls of the "measles, mumps, and rubella" - autism controversy: A narrative review.EXCLI journal · 2026Review
- Phase-specific sequential press-needle therapy for menstrual migraine: a randomized trial protocol.Frontiers in neurology · 2026Article
- Redefining Chemotherapy-Related Headaches: From Pathobiology to Differential Diagnosis and Management.International journal of molecular sciences · 2025Review
- Association between premenstrual syndrome or premenstrual dysphoric disorder and presence of ASD or ADHD among adolescent females: a retrospective study.Archives of women's mental health · 2025Article
- Article
- The Menstrual Cycle as a Vital Sign: a comprehensive review.F&S reviews · 2025Article
- Women's Pain Management Across the Lifespan-A Narrative Review of Hormonal, Physiological, and Psychosocial Perspectives.Journal of clinical medicine · 2025Review
- The role and interaction of hypothalamic-related neurotransmitters in migraine.The journal of headache and pain · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Migraine is a major neurological disorder affecting one in nine adults worldwide with a significant impact on health care and socioeconomic systems. Migraine is more prevalent in women than in men, with 17% of all women meeting the diagnostic criteria for migraine. In women, the frequency of migraine attacks shows variations over the menstrual cycle and pregnancy, and the use of combined hormonal contraception (CHC) or hormone replacement therapy (HRT) can unveil or modify migraine disease. In the general population, 18-25% of female migraineurs display a menstrual association of their headache. Here we present an overview on the evidence supporting the role of reproductive hormones, in particular estrogens, in the pathophysiology of migraine. We also analyze the efficacy and safety of prescribing exogenous estrogens as a potential treatment for menstrual-related migraine. Finally, we point to controversial issues and future research areas in the field of reproductive hormones and migraine.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.