Evidence map›Paper›PMID 35456015›Full record

ReviewCells2022

Impact of microRNA Regulated Macrophage Actions on Adipose Tissue Function in Obesity.

Alyssa Matz, Lili Qu, Keaton Karlinsey, Beiyan Zhou

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Cells, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Review
  3. The development of COVID-19 treatment.Frontiers in immunology · 2023
    Review
  4. Review
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Alyssa MatzDepartment of Immunology, School of Medicine, University of Connecticut, Farmington, CT 06030, USA.ORCID 0000-0003-0310-5097
Lili QuDepartment of Immunology, School of Medicine, University of Connecticut, Farmington, CT 06030, USA.ORCID 0000-0002-5253-6742
Keaton KarlinseyDepartment of Immunology, School of Medicine, University of Connecticut, Farmington, CT 06030, USA.ORCID 0000-0001-9085-4533
Beiyan ZhouDepartment of Immunology, School of Medicine, University of Connecticut, Farmington, CT 06030, USA.ORCID 0000-0003-0638-2428
University of Connecticut · US

Funding

MiR-150 regulated adiose tissue B cells in obesityR01DK121805 · NIDDK · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI VELLA, ANTHONY T, ZHOU, BEIYAN · 2020 to 2024
$2.0M
NIDDK NIH HHS R01 DK121805
6 · The paper itself

Abstract

Obesity-induced adipose tissue dysfunction is bolstered by chronic, low-grade inflammation and impairs systemic metabolic health. Adipose tissue macrophages (ATMs) perpetuate local inflammation but are crucial to adipose tissue homeostasis, exerting heterogeneous, niche-specific functions. Diversified macrophage actions are shaped through finely regulated factors, including microRNAs, which post-transcriptionally alter macrophage activation. Numerous studies have highlighted microRNAs' importance to immune function and potential as inflammation-modulatory. This review summarizes current knowledge of regulatory networks governed by microRNAs in ATMs in white adipose tissue under obesity stress.

Indexed as

MicroRNAsAdipose TissueHumansInflammationMacrophagesObesityMicroRNAsimmune responsemacrophagemicroRNAobesity

Identifiers

PMID35456015
PMCPMC9024513
OpenAlexW4224013007

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.