Evidence map›Paper›PMID 35455938›Full record

ArticleCells2022

Decellularized Organ-Derived Scaffold Is a Promising Carrier for Human Induced Pluripotent Stem Cells-Derived Hepatocytes.

Hideaki Kojima, Hiroshi Yagi, Hiroko Kushige, Yukiko Toda, Kazuo Takayama, Shinako Masuda, Toshinori Morisaku, Tomonori Tsuchida, Kohei Kuroda, Kazuya Hirukawa and 13 more

Open access · goldAbstract read
In one paragraph

Article in Cells, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. iPSC-derived cells for whole liver bioengineering.Frontiers in bioengineering and biotechnology · 2024
    Review
  6. Article
  7. Article
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors at 5 institutions in 1 country.

Hideaki KojimaDepartment of Surgery, Keio University School of Medicine, Shinanomachi 35, Shinjuku 162-8666, Japan.
Hiroshi YagiDepartment of Surgery, Keio University School of Medicine, Shinanomachi 35, Shinjuku 162-8666, Japan.ORCID 0000-0002-9897-8108
Hiroko KushigeDepartment of Surgery, Keio University School of Medicine, Shinanomachi 35, Shinjuku 162-8666, Japan.
Yukiko TodaLaboratory of Biochemistry and Molecular Biology, Graduate School of Pharmaceutical Sciences, Osaka University, Suita 565-0871, Japan.
Kazuo TakayamaLaboratory of Biochemistry and Molecular Biology, Graduate School of Pharmaceutical Sciences, Osaka University, Suita 565-0871, Japan.
Shinako MasudaInstitute of Advanced BioMedical Engineering and Science, Tokyo Women's Medical University, Shinjuku 162-8666, Japan.
Toshinori MorisakuDepartment of Surgery, Keio University School of Medicine, Shinanomachi 35, Shinjuku 162-8666, Japan.
Tomonori TsuchidaDepartment of Surgery, Keio University School of Medicine, Shinanomachi 35, Shinjuku 162-8666, Japan.
Kohei KurodaDepartment of Surgery, Keio University School of Medicine, Shinanomachi 35, Shinjuku 162-8666, Japan.
Kazuya HirukawaDepartment of Surgery, Keio University School of Medicine, Shinanomachi 35, Shinjuku 162-8666, Japan.
Jumpei InuiLaboratory of Biochemistry and Molecular Biology, Graduate School of Pharmaceutical Sciences, Osaka University, Suita 565-0871, Japan.
Kotaro NishiDepartment of Surgery, Keio University School of Medicine, Shinanomachi 35, Shinjuku 162-8666, Japan.ORCID 0000-0002-4961-2038
Yutaka NakanoDepartment of Surgery, Keio University School of Medicine, Shinanomachi 35, Shinjuku 162-8666, Japan.
Masayuki TanakaDepartment of Surgery, Keio University School of Medicine, Shinanomachi 35, Shinjuku 162-8666, Japan.
Shutaro HoriDepartment of Surgery, Keio University School of Medicine, Shinanomachi 35, Shinjuku 162-8666, Japan.
Yasushi HasegawaDepartment of Surgery, Keio University School of Medicine, Shinanomachi 35, Shinjuku 162-8666, Japan.ORCID 0000-0002-4990-0419
Yuta AbeDepartment of Surgery, Keio University School of Medicine, Shinanomachi 35, Shinjuku 162-8666, Japan.
Minoru KitagoDepartment of Surgery, Keio University School of Medicine, Shinanomachi 35, Shinjuku 162-8666, Japan.ORCID 0000-0002-4909-1199
Shungo AdachiMolecular Profiling Research Center for Drug Discovery, National Institute of Advanced Industrial Science and Technology, Aomi 2-4-7, Koto 162-8666, Japan.ORCID 0000-0001-5232-411X
Masatoshi TomiDivision of Pharmaceutics, Faculty of Pharmacy, Keio University, Shibakoen 1-5-30, Minato 162-8666, Japan.
Katsuhisa MatsuuraInstitute of Advanced BioMedical Engineering and Science, Tokyo Women's Medical University, Shinjuku 162-8666, Japan.
Hiroyuki MizuguchiLaboratory of Biochemistry and Molecular Biology, Graduate School of Pharmaceutical Sciences, Osaka University, Suita 565-0871, Japan.
Yuko KitagawaDepartment of Surgery, Keio University School of Medicine, Shinanomachi 35, Shinjuku 162-8666, Japan.
Keio University · JPThe University of Osaka · JPTokyo Women's Medical University · JPNational Institute of Advanced Industrial Science and Technology · JPNational Institute of Biomedical Innovation, Health and Nutrition · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human induced pluripotent stem cells (hiPSCs) are a promising cell source for elucidating disease pathology and therapy. The mass supply of hiPSC-derived cells is technically feasible. Carriers that can contain a large number of hiPSC-derived cells and evaluate their functions in vivo-like environments will become increasingly important for understanding disease pathogenesis or treating end-stage organ failure. hiPSC-derived hepatocyte-like cells (hiPSC-HLCs; 5 × 10

Indexed as

Induced Pluripotent Stem CellsAnimalsCell DifferentiationHepatocytesHumansRegenerative MedicineSwinedecellularizationextracellular matrixhuman iPSCsmicrominiature pigorgan-derived scaffoldxeno-implantationxeno-transplantation

Identifiers

PMID35455938
PMCPMC9025569
OpenAlexW4224237009

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.