Evidence map›Paper›PMID 35455720›Full record

ArticleJournal of personalized medicine2022

Development of Personalized Non-Invasive Ventilation Interfaces for Neonatal and Pediatric Application Using Additive Manufacturing.

Marit Bockstedte, Alexander B Xepapadeas, Sebastian Spintzyk, Christian F Poets, Bernd Koos, Maite Aretxabaleta

Open access · goldAbstract read
In one paragraph

Article in Journal of personalized medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Pediatrics 4.0: the Transformative Impacts of the Latest Industrial Revolution on Pediatrics.Health care analysis : HCA : journal of health philosophy and policy · 2025
    Article
  4. Article
  5. Review
  6. Indications and techniques of non-invasive ventilation (NIV) in neuromuscular diseases.Acta myologica : myopathies and cardiomyopathies : official journal of the Mediterranean Society of Myology · 2024
    Review
  7. Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Marit BockstedteDepartment of Orthodontics, University Centre of Dentistry, Oral Medicine and Maxillofacial Surgery within the University Hospital Tübingen, Osianderstr. 2-8, 72076 Tübingen, Germany.ORCID 0000-0003-3350-0290
Alexander B XepapadeasDepartment of Orthodontics, University Centre of Dentistry, Oral Medicine and Maxillofacial Surgery within the University Hospital Tübingen, Osianderstr. 2-8, 72076 Tübingen, Germany.ORCID 0000-0003-1645-929X
Sebastian SpintzykSection Medical Materials Science and Technology, University Hospital Tübingen, Osianderstr. 2-8, 72076 Tübingen, Germany.
Christian F PoetsDepartment of Neonatology, University Children's Hospital, Calwerstr. 7, 72076 Tübingen, Germany.ORCID 0000-0002-1072-0066
Bernd KoosDepartment of Orthodontics, University Centre of Dentistry, Oral Medicine and Maxillofacial Surgery within the University Hospital Tübingen, Osianderstr. 2-8, 72076 Tübingen, Germany.
Maite AretxabaletaDepartment of Orthodontics, University Centre of Dentistry, Oral Medicine and Maxillofacial Surgery within the University Hospital Tübingen, Osianderstr. 2-8, 72076 Tübingen, Germany.ORCID 0000-0002-9618-5016
University of Tübingen · DEUniversity Children's Hospital Tübingen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The objective of this study was to present a methodology and manufacturing workflow for non-invasive ventilation interfaces (NIV) for neonates and small infants. It aimed to procure a fast and feasible solution for personalized NIV produced in-house with the aim of improving fit and comfort for the patient. Three-dimensional scans were obtained by means of an intraoral (Trios 3) and a facial scanner (3dMd Flex System). Fusion 360 3D-modelling software was employed to automatize the design of the masks and their respective casting molds. These molds were additively manufactured by stereolithography (SLA) and fused filament fabrication (FFF) technologies. Silicone was poured into the molds to produce the medical device. In this way, patient individualized oronasal and nasal masks were produced. An automated design workflow and use of additive manufacturing enabled a fast and feasible procedure. Despite the cost for individualization likely being higher than for standard masks, a user-friendly workflow for in-house manufacturing of these medical appliances proved to have potential for improving NIV in neonates and infants, as well as increasing comfort.

Indexed as

craniofacial malformationscustomized medical devicedesign and manufacturing workflowfacial scanningintraoral scanningrapid toolingventilation mask

Identifiers

PMID35455720
PMCPMC9026706
OpenAlexW4224300249

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.