Evidence map›Paper›PMID 35455652›Full record

ArticleJournal of personalized medicine2022

The Maintained Glycemic Target Goal and Renal Function Are Associated with Cardiovascular and Renal Outcomes in Diabetic Patients Following Stent-Supported Angioplasty for Renovascular Atherosclerotic Disease.

Rafał Badacz, Anna Kabłak-Ziembicka, Agnieszka Rosławiecka, Daniel Rzeźnik, Jakub Baran, Mariusz Trystuła, Jacek Legutko, Tadeusz Przewłocki

Open access · goldAbstract read
In one paragraph

Article in Journal of personalized medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 10 citations in OpenAlex.

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  3. Observational
  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Rafał BadaczDepartment of Interventional Cardiology, Institute of Cardiology, Medical College, Jagiellonian University, 31-008 Krakow, Poland.ORCID 0000-0003-0122-1318
Anna Kabłak-ZiembickaDepartment of Interventional Cardiology, Institute of Cardiology, Medical College, Jagiellonian University, 31-008 Krakow, Poland.ORCID 0000-0002-8006-7840
Agnieszka RosławieckaDepartment of Interventional Cardiology, The John Paul II Hospital, 31-202 Krakow, Poland.
Daniel RzeźnikDepartment of Interventional Cardiology, Institute of Cardiology, Medical College, Jagiellonian University, 31-008 Krakow, Poland.
Jakub BaranDepartment of Interventional Cardiology, Institute of Cardiology, Medical College, Jagiellonian University, 31-008 Krakow, Poland.ORCID 0000-0002-0747-1468
Mariusz TrystułaDepartment of Vascular and Endovascular Surgery, John Paul II Hospital, 31-202 Krakow, Poland.
Jacek LegutkoDepartment of Interventional Cardiology, Institute of Cardiology, Medical College, Jagiellonian University, 31-008 Krakow, Poland.
Tadeusz PrzewłockiDepartment of Interventional Cardiology, The John Paul II Hospital, 31-202 Krakow, Poland.
Jagiellonian University · PLJohn Paul II Hospital · PL

Funding

Jagiellonian University K/ZDS/005730
6 · The paper itself

Abstract

Patients with type 2 diabetes mellitus (T2DM) constitute a large proportion of patients with atherosclerotic renal artery stenosis (ARAS). However, the mechanism of impaired renal function and hypertension in this subset of patients is multifactorial. We aimed to investigate whether, in diabetic patients, renal function (RF), systolic (SBP) and diastolic blood pressure (DBP) values following stent-supported angioplasty (PTA) for ARAS have an impact on cardiovascular and renal outcomes. Methods: The study group included 93 patients with T2DM and resistant hypertension who underwent PTA for ARAS. The pre- and post-procedure (6 to 12, and 24 months) values of SBP, DBP, eGFR and glycaemia were obtained. The prospective follow-up of median 44 months was performed for combined outcome: major cardiac and cerebral events (MACCE) and progression to renal replacement therapy (RRT). Results: MACCE-RRT occurred in 46 (49.5%) patients, with higher incidence in patients with higher values of SBP (147.8 ± 25.8 vs. 136.7 ± 15.8 mmHg, p = 0.006), DBP (80.8 ± 13.3 vs. 74.4 ± 12.3 mmHg, p = 0.009), chronic kidney disease in stages 3B to 5 (p = 0.029) and those who have not obtained target glycemic goals compared to well-maintained T2DM (p = 0.007) at 24-months. On multivariate Cox analysis, well-maintained T2DM targets [Hazard Ratio (HR):0.27; 95% Confidence Interval (CI):0.13−0.57; p < 0.001], eGFR below 45 mL/min/m2 (HR: 2.20; 95%CI: 1.20−4.04; p = 0.011), previous stroke (HR:2.52; 95%CI:1.19−5.34; p = 0.015) retained their associations with MACCE-RRT, while BP values were not associated with the outcome. Conclusions: The post-procedural RF, maintained glycemic target goal and previous stroke are vital for the outcome in patients undergoing PTA for renovascular disease in diabetic patients.

Indexed as

arterial occlusive diseaseblood pressurecardiovascular and renal outcomeschronic kidney diseaseendovascular proceduresrenal arterystentstarget glycemic goalstype 2 diabetes mellitus

Identifiers

PMID35455652
PMCPMC9028557
OpenAlexW4220747058

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.