ReviewJournal of personalized medicine2022
Endoscopic Combined Intrarenal Surgery Versus Percutaneous Nephrolithotomy for Complex Renal Stones: A Systematic Review and Meta-Analysis.
Review in Journal of personalized medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06085794 (Comparative Study Between Standard PCNL and Endoscopic Combined Intrarenal Surgery), which is not on this map. Cited by 17 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Comparative Study Between Standard PCNL and Endoscopic Combined Intrarenal Surgery (ECIRS) in the Galdakaomodified Supine Valdivia (GMSV) Position for Complex Nephrolithiasis in Obese Patients
Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 31 citations in OpenAlex.
- Hybrid endoscopic-robotic approaches for complex upper urinary tract disorders: a systematic review and single-arm meta-analysis.Journal of robotic surgery · 2025Pooled it
- International Alliance of Urolithiasis (IAU) guideline on staghorn calculi management.World journal of urology · 2024Guideline
- Antegrade flexible ureteroscopy-assisted percutaneous nephrolithotomy for staghorn calculi: a prospective randomized controlled study.Urolithiasis · 2024Trial
- Endoscopic combined intrarenal surgery: From percutaneous nephrolithotomy to the future of stone management.Investigative and clinical urology · 2026Review
- Feasibility and efficiency of the use of pulsed thulium: YAG (Thulio) laser for ECIRS: a multicenter evaluation.World journal of urology · 2026Article
- The benefits of PCNL combined with ureterorenoscopy compared to isolated PCNL in urolithiasis (PRECISE): a multicentre randomised controlled trial protocol.BJU international · 2026Article
- Retrograde pyeloperfusion: a novel technique to prevent stone fragment migration into the ureter during percutaneous nephrolithotomy.Urolithiasis · 2025Article
- Comparison of radiation exposure for interventional radiology vs urology-guided renal access for percutaneous nephrolithotomy.International urology and nephrology · 2025Article
- Endoscopic Combined Intrarenal Surgery for a Large Stone in a Rare Fused Supernumerary Kidney.Cureus · 2024Article
- Endoscopic combined intrarenal surgery for successful removal of an encrusted ureteral stent and multiple renal stones in solitary kidney: A case report.International journal of surgery case reports · 2024Article
- Nonpapillary Prone Endoscopic Combined Intrarenal Surgery (ECIRS): Five-Year Experience and Outcomes from a High-Volume Center.Journal of clinical medicine · 2024Article
- Endoscopic combined intrarenal surgery composed of micro-perc and retrograde intrarenal surgery in the treatment of complex kidney stones in children.World journal of urology · 2024Article
- Effect of flexible cystoscopy combined with flexible ureteroscopy on short-term outcomes in patients with complex renal stones.American journal of translational research · 2024Article
- Single-Center Experience with Swiss LithoClastDiagnostics (Basel, Switzerland) · 2023Article
- Percutaneous Nephrolithotomy Combined Antegrade Flexible Ureteroscope for Complete Staghorn Stones: A Case Report of a New Concept of Stone Surgery.Medicina (Kaunas, Lithuania) · 2022Article
- Current role of endoscopic combined intrarenal surgery in the management of renal stones: A scoping review.Indian journal of urology : IJU : journal of the Urological Society of IndiaArticle
- Endoscopic Combined Intrarenal Surgery: best practices and future perspectives.International braz j urol : official journal of the Brazilian Society of UrologyReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEndoscopic combined intrarenal surgery (ECIRS) adds ureteroscopic vision to percutaneous nephrolithotomy (PCNL), which can be helpful when dealing with complex renal stones. Yet, there is still no consensus on the superiority of ECIRS. We aimed to critically analyze the available evidence of studies comparing efficacy, safety, bleeding risk, and efficiency of ECIRS and PCNL.
methodsWe searched for studies comparing efficacy (initial and final stone-free rate), safety (postoperative fever, overall and severe complications), efficiency (operative time and hospital stay) and bleeding risk between ECIRS and PCNL. Meta-analysis was performed.
resultsSeven studies (919 patients) were identified. ECIRS provided a significantly higher initial stone-free rate, higher final stone-free rate, lower overall complications, lower severe complications, and lower rate of requiring blood transfusion. There was no difference between the two groups in terms of postoperative fever, hemoglobin drop, operative time, and hospital stay. In the subgroup analysis, both minimally invasive and conventional ECIRS were associated with a higher stone-free rate and lower complication outcomes.
conclusionsWhen treating complex renal stones, ECIRS has a better stone-free rate, fewer complications, and requires fewer blood transfusions compared with PCNL. Subgroups either with minimally invasive or conventional intervention showed a consistent trend.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.