Evidence map›Paper›PMID 35455620›Full record

ArticleChildren (Basel, Switzerland)2022

Liver and Pancreatic Involvement in Children with Multisystem Inflammatory Syndrome Related to SARS-CoV-2: A Monocentric Study.

Antonietta Giannattasio, Marco Maglione, Carolina D'Anna, Stefania Muzzica, Serena Pappacoda, Selvaggia Lenta, Onorina Di Mita, Giusy Ranucci, Claudia Mandato, Vincenzo Tipo

Open access · goldAbstract read
In one paragraph

Article in Children (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Antonietta GiannattasioPediatric Emergency Unit, Santobono-Pausilipon Children's Hospital, AORN, 80130 Naples, Italy.ORCID 0000-0001-8073-7114
Marco MaglionePediatric Emergency Unit, Santobono-Pausilipon Children's Hospital, AORN, 80130 Naples, Italy.ORCID 0000-0001-8181-2219
Carolina D'AnnaPediatric Emergency Unit, Santobono-Pausilipon Children's Hospital, AORN, 80130 Naples, Italy.
Stefania MuzzicaPediatric Emergency Unit, Santobono-Pausilipon Children's Hospital, AORN, 80130 Naples, Italy.
Serena PappacodaPediatric Emergency Unit, Santobono-Pausilipon Children's Hospital, AORN, 80130 Naples, Italy.
Selvaggia LentaPediatric Emergency Unit, Santobono-Pausilipon Children's Hospital, AORN, 80130 Naples, Italy.
Onorina Di MitaPediatric Emergency Unit, Santobono-Pausilipon Children's Hospital, AORN, 80130 Naples, Italy.
Giusy RanucciPediatric Emergency Unit, Santobono-Pausilipon Children's Hospital, AORN, 80130 Naples, Italy.
Claudia MandatoMedical Department, University of Salerno, 84084 Salerno, Italy.ORCID 0000-0003-2425-5449
Vincenzo TipoPediatric Emergency Unit, Santobono-Pausilipon Children's Hospital, AORN, 80130 Naples, Italy.
Santobono Children's Hospital · ITUniversity of Salerno · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Liver and pancreatic involvement in children with Multisystem Inflammatory Syndrome related to SARS-CoV-2 (MIS-C) has been poorly investigated so far. We reviewed a cohort of MIS-C patients to analyze the prevalence of acute liver injury (ALI) and pancreatic injury and their correlation with clinical outcomes. Demographic, clinical, laboratory and imaging features of children with MIS-C at admission and during hospital stay were prospectively collected. Fifty-five patients (mean age 6.5 ± 3.7 years) were included. At admission, 16 patients showed ALI and 5 had increased total serum lipase. During observation, 10 more patients developed ALI and 19 more subjects presented raised pancreatic enzymes. In comparison to those with normal ALT, subjects with ALI were significantly older (

Indexed as

acute liver injurychildrenmultisystem inflammatory syndrome related to SARS-CoV-2pancreatic injuryprognosis

Identifiers

PMID35455620
PMCPMC9029098
OpenAlexW4224261859

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.