Evidence map›Paper›PMID 35455523›Full record

ArticleChildren (Basel, Switzerland)2022

The Impact of Clinical Pharmacy Services in a Tertiary Care Center Specialized in Pediatric Hemato-Oncology.

Christina Gradwohl, Gernot Engstler, Martina Anditsch, Herbert Pichler, Gunar Stemer

Abstract read
In one paragraph

Article in Children (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Christina GradwohlSt. Anna Children's Hospital, Department of Paediatrics, Medical University of Vienna, 1090 Vienna, Austria.ORCID 0000-0002-5918-1251
Gernot EngstlerSt. Anna Children's Hospital, Department of Paediatrics, Medical University of Vienna, 1090 Vienna, Austria.
Martina AnditschPharmacy Department, University Hospital AKH, 1090 Vienna, Austria.
Herbert PichlerSt. Anna Children's Hospital, Department of Paediatrics, Medical University of Vienna, 1090 Vienna, Austria.ORCID 0000-0001-5107-5123
Gunar StemerPharmacy Department, University Hospital AKH, 1090 Vienna, Austria.ORCID 0000-0001-9647-315X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Clinical pharmacy services (CPS) have shown beneficial effects on several outcome measures in hospital patients, including the reduction of drug-related problems (DRP) and of therapy costs. Less is known about the impact of CPS in pediatric haemato-oncology, even though this patient population is highly susceptible to DRP. CPS were implemented in a tertiary care children's hospital specialized in hemato-oncology and hematopoietic stem cell transplantation. The main outcome measures were type and number of DRP, type and number of pharmaceutical interventions (PI), their acceptance rate, and their clinical significance and economic benefit. During 6 months and 32 ward rounds, 275 DRP were identified and addressed by PI. The acceptance of PI was high (73.4%), and up to 80% of PI were rated as very significant or significant by independent external raters. The estimated therapy cost reductions were substantial, approaching at least EUR 54,600 for avoided follow-up costs. Conclusion: CPS improve medication safety in pediatric hemato-oncology and may reduce therapy costs.

Indexed as

clinical pharmacy servicesdrug-related problemshematologyhematopoietic stem cell transplantationoncologypediatrics

Identifiers

PMID35455523
PMCPMC9025946

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.