ReviewChildren (Basel, Switzerland)2022
Making Hardware Removal Unnecessary by Using Resorbable Implants for Osteosynthesis in Children.
Review in Children (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 33 citations in OpenAlex.
- Waste Generation in Pediatric Orthopaedic Hardware Removal Surgery.Journal of the Pediatric Orthopaedic Society of North America · 2026Article
- Biodegradable (PLGA) Implants in Pediatric Trauma: A Brief Review.Children (Basel, Switzerland) · 2025Review
- Complication profile and risk patterns following elective implant removal in pediatric fractures: a 10-year retrospective analysis.Journal of orthopaedic surgery and research · 2025Article
- Application of biodegradable implants in pediatric orthopedics: shifting from absorbable polymers to biodegradable metals.Bioactive materials · 2025Article
- Physico-mechanical characterization of 3D-printed PLGA for patient-specific resorbable implants in craniofacial surgery.Scientific reports · 2025Article
- Degradable poly-lactic-co-glycolic acid and non-degradable polymer implants result in similar fracture healing at early timepoints.Clinical biomechanics (Bristol, Avon) · 2025Article
- Comparison of Titanium versus Resorbable Intramedullary Nailing in Pediatric Forearm Fractures.Children (Basel, Switzerland) · 2024Article
- Pediatric Diaphyseal Forearm Fracture Management with Biodegradable Poly-L-Lactide-Co-Glycolide (PLGA) Intramedullary Implants: A Longitudinal Study.Journal of clinical medicine · 2024Article
- Characterization of degradation kinetics of additively manufactured PLGA under variable mechanical loading paradigms.Journal of the mechanical behavior of biomedical materials · 2024Article
- Resorbable Patient-Specific Implants of Molybdenum for Pediatric Craniofacial Surgery-Proof of Concept in an In Vivo Pilot Study.Journal of functional biomaterials · 2024Article
- Harnessing the Potential of PLGA Nanoparticles for Enhanced Bone Regeneration.Pharmaceutics · 2024Review
- Management of Juvenile Osteochondral Fractures Utilising Absorbable PLGA Implants.Journal of clinical medicine · 2024Article
- A Review on Polymers for Biomedical Applications on Hard and Soft Tissues and Prosthetic Limbs.Polymers · 2023Review
- High Complication Rate and High Percentage of Regressing Radiolucency in Magnesium Screw Fixation in 18 Consecutive Patients.Journal of personalized medicine · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionFollowing osteosynthesis, children generally require a second surgery to remove the hardware. This becomes unnecessary, by using resorbable implants. Limiting the number of required surgeries and their associated risks, this technique provides critical aspects of minimally invasive surgery. This review focuses on resorbable implants for osteosynthesis for the treatment of fractures in children and discusses their clinical features.
methodWe provide an overview of the two most common technologies used in resorbable osteosynthesis materials: polymer- and magnesium-based alloys. Clinical examples of osteosynthesis are presented using polymer-based ActivaTM products and magnesium-based Magnezix
resultsPolymer-based implants demonstrate surgical safety and efficacy. Due to their elasticity, initial placement of polymer-based products may demonstrate technical challenges. However, stability is maintained over the course of healing. While maintaining good biocompatibility, the rate of polymer-resorption may be controlled by varying the composition of polyesters and copolymers. Similarly, magnesium-based implants demonstrate good mechanical stability and resorption rates, while these characteristics may be controlled by varying alloy components. One of the significant shortcomings of magnesium is that metabolism results in the production of hydrogen gas. Both technologies provide equally good results clinically and radiographically, when compared to non-resorbable implants.
conclusionResorbable osteosynthesis materials demonstrate similar therapeutic results as conventional materials for osteosynthesis. Resorbable implants may have the potential to improve patient outcomes, by sparing children a second surgery for hardware removal.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.