Evidence map›Paper›PMID 35455403›Full record

ArticlePharmaceuticals (Basel, Switzerland)2022

Improvement of Biocatalytic Properties and Cytotoxic Activity of L-Asparaginase from

Natalia V Dobryakova, Dmitry D Zhdanov, Nikolay N Sokolov, Svetlana S Aleksandrova, Marina V Pokrovskaya, Elena V Kudryashova

Open access · goldAbstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Natalia V DobryakovaChemical Faculty, Lomonosov Moscow State University, Leninskie Gory St. 1, 119991 Moscow, Russia.
Dmitry D ZhdanovLaboratory of Medical Biotechnology, Institute of Biomedical Chemistry, Pogodinskaya St. 10/8, 119121 Moscow, Russia.ORCID 0000-0003-4753-7588
Nikolay N SokolovLaboratory of Medical Biotechnology, Institute of Biomedical Chemistry, Pogodinskaya St. 10/8, 119121 Moscow, Russia.
Svetlana S AleksandrovaLaboratory of Medical Biotechnology, Institute of Biomedical Chemistry, Pogodinskaya St. 10/8, 119121 Moscow, Russia.ORCID 0000-0002-4248-765X
Marina V PokrovskayaLaboratory of Medical Biotechnology, Institute of Biomedical Chemistry, Pogodinskaya St. 10/8, 119121 Moscow, Russia.
Elena V KudryashovaChemical Faculty, Lomonosov Moscow State University, Leninskie Gory St. 1, 119991 Moscow, Russia.ORCID 0000-0002-9761-7757
Institute of Biomedical Chemistry · RULomonosov Moscow State University · RUPeoples' Friendship University of Russia · RU

Funding

The Ministry of Education and Science of the Russian Federation FNME-2019-0003
6 · The paper itself

Abstract

L-asparaginases (L-ASNases, EC 3.5.1.1) are a family of enzymes that are widely used for the treatment of lymphoblastic leukemias. L-ASNase from

Indexed as

antitumor activitycatalytic activitycationic polymerscovalent conjugatesL-asparaginasepolyelectrolyte complexesRhodospirillum rubrum

Identifiers

PMID35455403
PMCPMC9029710
OpenAlexW4220876009

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.