Evidence map›Paper›PMID 35455378›Full record

ArticleVaccines2022

COVID-19 Neutralizing Antibodies in Breast Milk of Mothers Vaccinated with Three Different Vaccines in Mexico.

Olivia Cabanillas-Bernal, Karla Cervantes-Luevano, Gonzalo Isai Flores-Acosta, Johanna Bernáldez-Sarabia, Alexei F Licea-Navarro

Abstract read
In one paragraph

Article in Vaccines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Olivia Cabanillas-BernalBiosafety Laboratory Level 3, Biomedical Innovation Department, Ensenada Center for Scientific Research and Higher Education (CICESE), Ensenada 22860, Mexico.
Karla Cervantes-LuevanoBiosafety Laboratory Level 3, Biomedical Innovation Department, Ensenada Center for Scientific Research and Higher Education (CICESE), Ensenada 22860, Mexico.
Gonzalo Isai Flores-AcostaBiosafety Laboratory Level 3, Biomedical Innovation Department, Ensenada Center for Scientific Research and Higher Education (CICESE), Ensenada 22860, Mexico.
Johanna Bernáldez-SarabiaBiosafety Laboratory Level 3, Biomedical Innovation Department, Ensenada Center for Scientific Research and Higher Education (CICESE), Ensenada 22860, Mexico.
Alexei F Licea-NavarroBiosafety Laboratory Level 3, Biomedical Innovation Department, Ensenada Center for Scientific Research and Higher Education (CICESE), Ensenada 22860, Mexico.ORCID 0000-0003-4022-7405

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has caused the largest pandemic of this century, and all aspects of this virus are being studied. The efforts to mitigate the negative effects associated with the SARS-CoV-2 pandemic have culminated in the development of several vaccines that are effective and safe for use to the general population. However, one aspect that remains relatively underexplored is the efficacy of different vaccines technologies (mRNA and Adenovirus) in providing passive immunity to infants through breastmilk of vaccinated mothers, and whether the antibodies passed through breast milk are functional. In this study, using a Micro-neutralization assay, we evaluate the presence of neutralizing antibodies in breast milk of lactating mothers vaccinated against SARS-CoV-2 with the Pfizer-BioNtech, Johnson & Johnson (J&J)/Janssen, and CanSino Biologics vaccines. Our results show the greatest neutralizing effect in breast milk from mothers vaccinated with Pfizer, followed by mothers vaccinated with J&J. CanSino vaccinations yielded the breast milk with the least neutralizing effects. The results found in this study relating to the neutralizing capacity of breast milk against SARS-CoV-2 highlight the importance of corresponding health authorities recommending vaccination to lactating mothers and of the continuance of breastfeeding to infants due to the potential health benefits.

Indexed as

breast milkCOVID-19neutralizing antibodiesSARS-CoV-2vaccines

Identifiers

PMID35455378
PMCPMC9029061

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.