Evidence map›Paper›PMID 35455260›Full record

ArticleVaccines2022

Postvaccination SARS-CoV-2 Infections among Healthcare Professionals: A Real World Evidence Study.

Alessandro Perrella, Sara Mucherino, Ilaria Guarino, Mariagiovanna Nerilli, Alberto Enrico Maraolo, Nicolina Capoluongo, Enrico Coscioni, Ugo Trama, Enrica Menditto, Valentina Orlando

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Vaccines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Alessandro PerrellaUOC Emerging Infectious Disease with High Contagiousness, AORN Ospedali dei Colli P.O. C Cotugno, 80131 Naples, Italy.ORCID 0000-0003-2812-8500
Sara MucherinoCIRFF (Center of Drug Utilization and Pharmacoeconomics), Department of Pharmacy, University of Naples Federico II, 80131 Naples, Italy.ORCID 0000-0003-3357-5655
Ilaria GuarinoCIRFF (Center of Drug Utilization and Pharmacoeconomics), Department of Pharmacy, University of Naples Federico II, 80131 Naples, Italy.
Mariagiovanna NerilliUOC Emerging Infectious Disease with High Contagiousness, AORN Ospedali dei Colli P.O. C Cotugno, 80131 Naples, Italy.
Alberto Enrico MaraoloUOC Emerging Infectious Disease with High Contagiousness, AORN Ospedali dei Colli P.O. C Cotugno, 80131 Naples, Italy.ORCID 0000-0002-7218-7762
Nicolina CapoluongoUOC Emerging Infectious Disease with High Contagiousness, AORN Ospedali dei Colli P.O. C Cotugno, 80131 Naples, Italy.
Enrico CoscioniRegional Task Force COVID-19, Campania Region, 80143 Naples, Italy.
Ugo TramaRegional Task Force COVID-19, Campania Region, 80143 Naples, Italy.
Enrica MendittoCIRFF (Center of Drug Utilization and Pharmacoeconomics), Department of Pharmacy, University of Naples Federico II, 80131 Naples, Italy.
Valentina OrlandoCIRFF (Center of Drug Utilization and Pharmacoeconomics), Department of Pharmacy, University of Naples Federico II, 80131 Naples, Italy.ORCID 0000-0002-8209-8878
Ospedale D. Cotugno · ITUniversity of Naples Federico II · ITRegione Campania · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Due to the COVID-19 pandemic, all countries with a global mobilization started to produce and authorize vaccines, prioritizing healthcare professionals (HCPs) to reduce transmission. The aim of this study was to assess post-vaccination infections' occurrence among HCPs and their correlation with symptom onset. A retrospective cohort study was carried out in the Campania Region from December 2020 to April 2021. Data were retrieved from the Regional Health Information System of the Campania Region (Sinfonia). The study cohort included subjects that had all received at least one vaccine dose. Risk ratios (RRs) adjusted for age and sex (95% confidence intervals) were performed to assess differences in the prevalence between HCPs who tested positive or negative for COVID-19. Univariate and multivariate logistic regression models were used to evaluate the association between symptoms and vaccination status. Findings revealed that HCPs had a lower risk of contracting COVID-19 after receiving at least one vaccine dose, and this risk decreased with age. Furthermore, not having full vaccination coverage may predict a severe/critical evolution of the disease. This study provides a snapshot of the initial state of the Italian vaccination campaign on HCPs. A surveillance approach using Big Data matched to clinical conditions could offer a real analysis in the categorization of subjects most at risk.

Indexed as

COVID-19COVID-19 symptomshealthcare professionalshealthcare workersSARS-CoV-2vaccination

Identifiers

PMID35455260
PMCPMC9024651
OpenAlexW4221030958

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.