Evidence map›Paper›PMID 35455238›Full record

ArticleVaccines2022

Pivotal

Patricia B Pavlinac, Elizabeth T Rogawski McQuade, James A Platts-Mills, Karen L Kotloff, Carolyn Deal, Birgitte K Giersing, Richard A Isbrucker, Gagandeep Kang, Lyou-Fu Ma, Calman A MacLennan and 3 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Vaccines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06047821 (The Incidence and Burden of Shigella Diarrhea in Children Aged 6-35 Months), which is not on this map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06047821 active not recruitingnot on this map

The Incidence and Burden of Shigella Diarrhea in Children Aged 6-35 Months: the Enterics for Global Health (EFGH) - Shigella Burden Study

TypeobservationalSponsorUniversity of WashingtonRan2022 to 2025Enrolled9,800ConditionsShigella, Child, Diarrhea
3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Consequences of Shigella infection in young children: a systematic review.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2023
    Pooled it
  2. Human vaccines & immunotherapeutics · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Shigellosis.Lancet (London, England) · 2025
    Review
  7. Article
  8. Exploring Natural Immune Responses toOpen forum infectious diseases · 2024
    Article
  9. ExploringVaccine: X · 2023
    Article
  10. Article
  11. Review
  12. Article
  13. Toward aInternational journal of molecular sciences · 2023
    Review
  14. Frontiers inVaccines · 2022
    Article
  15. TheVaccines · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 8 institutions in 3 countries.

Patricia B PavlinacDepartments of Global Health and Epidemiology, University of Washington, Seattle, WA 98105, USA.ORCID 0000-0002-0051-9131
Elizabeth T Rogawski McQuadeDepartment of Epidemiology, Emory University, Atlanta, GA 30322, USA.ORCID 0000-0002-4942-3747
James A Platts-MillsDepartment of Medicine, Infectious Diseases and International Health, University of Virginia, Charlottesville, VA 22908, USA.
Karen L KotloffDepartment of Pediatrics, Medicine, Epidemiology, and Public Health, University of Maryland, Baltimore, MD 21201, USA.
Carolyn DealEnteric and Sexually Transmitted Infections Branch, National Institutes of Health, Rockvile, MD 20892, USA.
Birgitte K GiersingImmunization, Vaccines, and Biologicals Department, World Health Organization, 1211 Geneva, Switzerland.
Richard A IsbruckerImmunization, Vaccines, and Biologicals Department, World Health Organization, 1211 Geneva, Switzerland.
Gagandeep KangDepartment of Gastrointestinal Sciences, Christian Medical College, Vellore 632004, Tamil Nadu, India.
Lyou-Fu MaEnteric and Diarrheal Diseases Program Strategy Team, Bill & Melinda Gates Foundation, Seattle, WA 98102, USA.
Calman A MacLennanEnteric and Diarrheal Diseases Program Strategy Team, Bill & Melinda Gates Foundation, Seattle, WA 98102, USA.
Peter PatriarcaBill & Melinda Gates Medical Research Institute, Cambridge, MA 02139, USA.
Duncan SteeleEnteric and Diarrheal Diseases Program Strategy Team, Bill & Melinda Gates Foundation, Seattle, WA 98102, USA.ORCID 0000-0002-4946-037X
Kirsten S VanniceEnteric and Diarrheal Diseases Program Strategy Team, Bill & Melinda Gates Foundation, Seattle, WA 98102, USA.
Gates Foundation · USWorld Health Organization · CHChristian Medical College, Vellore · INEmory University · USNational Institutes of Health · USUniversity of Maryland, Baltimore · USUniversity of Virginia · USUniversity of Washington · US

Funding

Translation of epidemiologic findings in enteric disease to public health actionK01AI130326 · NIAID · UNIVERSITY OF VIRGINIA · PI ROGAWSKI MCQUADE, ELIZABETH TACKET · 2018 to 2022
$612k
NIAID NIH HHS K01 AI130326World Health Organization 001
6 · The paper itself

Abstract

Vaccine candidates for

Indexed as

low and middle-income countriespediatricsShigellavaccine trial design

Identifiers

PMID35455238
PMCPMC9032541
OpenAlexW4224319133

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.