Evidence map›Paper›PMID 35455010›Full record

ArticleLife (Basel, Switzerland)2022

Green Synthesis and Anticancer Potential of 1,4-Dihydropyridines-Based Triazole Derivatives: In Silico and In Vitro Study.

Sabera Bijani, Danish Iqbal, Sheefa Mirza, Vicky Jain, Sadaf Jahan, Mohammed Alsaweed, Yahya Madkhali, Suliman A Alsagaby, Saeed Banawas, Abdulrahman Algarni and 4 more

Open access · goldAbstract read
In one paragraph

Article in Life (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 7 institutions in 4 countries.

Sabera BijaniDepartment of Chemistry, Marwadi University, Rajkot 360005, Gujarat, India.
Danish IqbalDepartment of Medical Laboratory Sciences, College of Applied Medical Sciences, Majmaah University, Al Majmaah 11952, Saudi Arabia.ORCID 0000-0002-3033-4226
Sheefa MirzaDepartment of Internal Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg 2193, South Africa.
Vicky JainDepartment of Chemistry, Marwadi University, Rajkot 360005, Gujarat, India.
Sadaf JahanDepartment of Medical Laboratory Sciences, College of Applied Medical Sciences, Majmaah University, Al Majmaah 11952, Saudi Arabia.ORCID 0000-0002-6976-5672
Mohammed AlsaweedDepartment of Medical Laboratory Sciences, College of Applied Medical Sciences, Majmaah University, Al Majmaah 11952, Saudi Arabia.ORCID 0000-0002-3859-5455
Yahya MadkhaliDepartment of Medical Laboratory Sciences, College of Applied Medical Sciences, Majmaah University, Al Majmaah 11952, Saudi Arabia.
Suliman A AlsagabyDepartment of Medical Laboratory Sciences, College of Applied Medical Sciences, Majmaah University, Al Majmaah 11952, Saudi Arabia.ORCID 0000-0002-2242-5638
Saeed BanawasDepartment of Medical Laboratory Sciences, College of Applied Medical Sciences, Majmaah University, Al Majmaah 11952, Saudi Arabia.ORCID 0000-0002-4423-8892
Abdulrahman AlgarniDepartment of Medical Laboratory Technology, Faculty of Applied Medical Sciences, Northern Border University, Arar 91431, Saudi Arabia.
Faris AlrumaihiDepartment of Medical Laboratories, College of Applied Medical Sciences, Qassim University, Buraydah 51425, Saudi Arabia.ORCID 0000-0002-0850-5500
Rakesh M RawalDepartment of Life Sciences, Gujarat University, Ahmedabad 380009, Gujarat, India.
Wael AlturaikiDepartment of Medical Laboratory Sciences, College of Applied Medical Sciences, Majmaah University, Al Majmaah 11952, Saudi Arabia.ORCID 0000-0002-6947-7582
Anamik ShahCenter of Excellence, National Facility for Drug Discovery Complex, Department of Chemistry, Saurashtra University, Rajkot 360005, Gujarat, India.
Majmaah University · SASaurashtra University · INGujarat University · INNorthern Border University · SAOregon State University · USQassim University · SAUniversity of the Witwatersrand · ZA

Funding

Majmaah University xxx
6 · The paper itself

Abstract

A library of 1,4-dihydropyridine-based 1,2,3-triazol derivatives has been designed, synthesized, and evaluated their cytotoxic potential on colorectal adenocarcinoma (Caco-2) cell lines. All compounds were characterized and identified based on their

Indexed as

apoptosischeminformaticsclick chemistrycytotoxicitygreen synthesisprotein kinasetankyrase

Identifiers

PMID35455010
PMCPMC9029820
OpenAlexW4220969646

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.