ArticleLife (Basel, Switzerland)2022
Safety and Efficacy of Cone-Beam Computed Tomography-Guided Lung Tumor Localization with a Near-Infrared Marker: A Retrospective Study of 175 Patients.
Article in Life (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 10 citations in OpenAlex.
- Single-stage virtual-assisted lung mapping with mobile cone-beam CT confirmation followed by thoracoscopic sublobar lung resection.Surgical endoscopy · 2026Article
- Real-world localization of cancer in lungs with a commercially available folate receptor-targeted fluorescent agent for intraoperative molecular imaging.JTCVS techniques · 2025Article
- Localization strategies for deep lung nodule using electromagnetic navigation bronchoscopy and indocyanine green fluorescence: a technical note.Journal of thoracic disease · 2024Article
- Indocyanine green localization for preoperative CT-guided localization of multiple pulmonary nodules.Thoracic cancer · 2024Article
- Advantages and rational application of indocyanine green fluorescence in pulmonary nodule surgery: a narrative review.Journal of thoracic disease · 2024Review
- Current Status and Future Perspectives of Preoperative and Intraoperative Marking in Thoracic Surgery.Cancers · 2024Review
- State of the Art in Lung Nodule Localization.Journal of clinical medicine · 2022Review
- How effective is indocyanine green (ICG) in localization of malignant pulmonary nodules? A systematic review and meta-analysis.Frontiers in surgery · 2022Review
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
Preoperative localization holds promise for overcoming the limitations of video-assisted thoracoscopic surgery (VATS) in the treatment of impalpable lung nodules. The purpose of this study was to assess the safety and efficacy of cone-beam computed tomography (CBCT)-guided localization using near-infrared (NIR) marking. Between 2017 and 2021, patients presenting with a solitary pulmonary nodule (SPN) who had undergone CBCT-guided lesion localization with indocyanine green (ICG) in a hybrid operating room were included. The primary outcomes were the efficacy of localization and the occurrence of complications. The study cohort consisted of 175 patients with the mean age of 58.76 years. The mean size and depth of the 175 SPNs were 8.34 mm and 5.3 mm, respectively. The mean time required for lesion marking was 14.71 min. Upon thoracoscopic inspection, the NIR tattoo was detected in the vast majority of the study participants (98.3%). An utility thoracotomy to allow digital palpation was required in two of the three patients in whom the tattoo was not identifiable. The perioperative survival rate was 100%, and the mean length of hospital stay was 3.09 days. We conclude that needle localization with ICG injection is a safe and feasible technique to localize SPNs prior to resection.
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