Evidence map›Paper›PMID 35454528›Full record

ArticleMaterials (Basel, Switzerland)2022

Preparation, Characterization, Solubility, and Antioxidant Capacity of Ellagic Acid-Urea Complex.

Hitomi Sakurai, Mitsuaki Suzuki, Shoko Itakura, Hiroaki Todo, Florencio Arce, Gerard Lee See, Takashi Tanikawa, Yutaka Inoue

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Materials (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hitomi SakuraiFaculty of Pharmacy and Pharmaceutical Sciences, Josai University, 1-1 Keyakidai, Sakado 3500295, Saitama, Japan.
Mitsuaki SuzukiFaculty of Science, Josai University, 1-1 Keyakidai, Sakado 3500295, Saitama, Japan.
Shoko ItakuraFaculty of Pharmacy and Pharmaceutical Sciences, Josai University, 1-1 Keyakidai, Sakado 3500295, Saitama, Japan.
Hiroaki TodoFaculty of Pharmacy and Pharmaceutical Sciences, Josai University, 1-1 Keyakidai, Sakado 3500295, Saitama, Japan.ORCID 0000-0003-0091-4366
Florencio ArcePharmaceutical Research & Drug Development Laboratories, Department of Pharmacy, School of Health Care Professions, University of San Carlos, Cebu 6000, Philippines.
Gerard Lee SeePharmaceutical Research & Drug Development Laboratories, Department of Pharmacy, School of Health Care Professions, University of San Carlos, Cebu 6000, Philippines.
Takashi TanikawaFaculty of Pharmacy and Pharmaceutical Sciences, Josai University, 1-1 Keyakidai, Sakado 3500295, Saitama, Japan.
Yutaka InoueFaculty of Pharmacy and Pharmaceutical Sciences, Josai University, 1-1 Keyakidai, Sakado 3500295, Saitama, Japan.ORCID 0000-0003-3419-343X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ellagic acid (EA), a natural polyphenol found in berries, has high antioxidant capacity. This study aimed to improve EA solubility by complex formation with urea (UR) using solvent evaporation method and evaluate its solubility, antioxidant capacity, and physical properties. The solubility test (25 °C, 72 h) showed that the solubility of EVP (EA/UR = 1/1) was approximately two-fold higher than that of EA (7.13 µg/mL versus 3.99 µg/mL). Moreover, the IC

Indexed as

antioxidant capacitycomplex formationellagic acidsolubilityurea

Identifiers

PMID35454528
PMCPMC9032788

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.