Evidence map›Paper›PMID 35454144›Full record

ReviewBiomolecules2022

Long COVID-19 in Children: From the Pathogenesis to the Biologically Plausible Roots of the Syndrome.

Michele Piazza, Maria Di Cicco, Luca Pecoraro, Michele Ghezzi, Diego Peroni, Pasquale Comberiati

Open access · goldAbstract readReview
In one paragraph

Review in Biomolecules, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Observational
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Long COVID in Children: A Multidisciplinary Review.Diagnostics (Basel, Switzerland) · 2023
    Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Michele PiazzaDepartment of Surgery, Dentistry, Pediatrics and Gynecology, University of Verona, 37126 Verona, Italy.ORCID 0000-0001-7746-8267
Maria Di CiccoDepartment of Clinical and Experimental Medicine, Section of Pediatrics, University of Pisa, 56126 Pisa, Italy.ORCID 0000-0002-7027-6817
Luca PecoraroDepartment of Surgery, Dentistry, Pediatrics and Gynecology, University of Verona, 37126 Verona, Italy.ORCID 0000-0002-9765-8006
Michele GhezziAllergology and Pneumology Unit, V. Buzzi Children's Hospital, 20154 Milan, Italy.ORCID 0000-0002-7434-9112
Diego PeroniDepartment of Clinical and Experimental Medicine, Section of Pediatrics, University of Pisa, 56126 Pisa, Italy.ORCID 0000-0002-0234-1373
Pasquale ComberiatiDepartment of Clinical and Experimental Medicine, Section of Pediatrics, University of Pisa, 56126 Pisa, Italy.ORCID 0000-0001-5209-9733
University of Pisa · ITUniversity of Verona · ITOspedale dei Bambini Vittore Buzzi · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Long Coronavirus disease-19 (COVID-19) refers to the persistence of symptoms related to the infection with severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2). This condition is described as persistent and can manifest in various combinations of signs and symptoms, such as fatigue, headache, dyspnea, depression, cognitive impairment, and altered perception of smells and tastes. Long COVID-19 may be due to long-term damage to different organs-such as lung, brain, kidney, and heart-caused by persisting viral-induced inflammation, immune dysregulation, autoimmunity, diffuse endothelial damage, and micro thrombosis. In this review, we discuss the potential and biologically plausible role of some vitamins, essential elements, and functional foods based on the hypothesis that an individual's dietary status may play an important adjunctive role in protective immunity against COVID-19 and possibly against its long-term consequences.

Indexed as

COVID-19ChildHumansInflammationPost-Acute COVID-19 SyndromeSARS-CoV-2VitaminsVitaminsantioxidantCOVID-19long-COVIDmagnesiumoxidative stressSARS-CoV-2seleniumvitamin Dvitaminszinc

Identifiers

PMID35454144
PMCPMC9024951
OpenAlexW4224282515

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.