Evidence map›Paper›PMID 35454109›Full record

ArticleBiomolecules2022

Darling: A Web Application for Detecting Disease-Related Biomedical Entity Associations with Literature Mining.

Evangelos Karatzas, Fotis A Baltoumas, Ioannis Kasionis, Despina Sanoudou, Aristides G Eliopoulos, Theodosios Theodosiou, Ioannis Iliopoulos, Georgios A Pavlopoulos

Abstract read
In one paragraph

Article in Biomolecules, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Arena3DNAR genomics and bioinformatics · 2023
    Article
  8. Review
  9. Review
  10. In Vitro Anti-Influenza Virus Activity of Non-PolarPharmaceuticals (Basel, Switzerland) · 2022
    Article
  11. Prediction and Ranking of Biomarkers UsingInternational journal of molecular sciences · 2022
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Evangelos KaratzasInstitute for Fundamental Biomedical Research, Biomedical Sciences Research Center "Alexander Fleming", 16672 Vari, Greece.ORCID 0000-0001-9132-8981
Fotis A BaltoumasInstitute for Fundamental Biomedical Research, Biomedical Sciences Research Center "Alexander Fleming", 16672 Vari, Greece.ORCID 0000-0002-2870-2931
Ioannis KasionisInstitute for Fundamental Biomedical Research, Biomedical Sciences Research Center "Alexander Fleming", 16672 Vari, Greece.
Despina SanoudouClinical Genomics and Pharmacogenomics Unit, 4th Department of Internal Medicine, School of Medicine, National and Kapodistrian University of Athens, 11527 Athens, Greece.ORCID 0000-0003-3704-1941
Aristides G EliopoulosCenter for New Biotechnologies and Precision Medicine, School of Medicine, National and Kapodistrian University of Athens, 11527 Athens, Greece.ORCID 0000-0002-6403-6761
Theodosios TheodosiouDepartment of Basic Sciences, School of Medicine, University of Crete, 71003 Heraklion, Greece.
Ioannis IliopoulosDepartment of Basic Sciences, School of Medicine, University of Crete, 71003 Heraklion, Greece.
Georgios A PavlopoulosInstitute for Fundamental Biomedical Research, Biomedical Sciences Research Center "Alexander Fleming", 16672 Vari, Greece.ORCID 0000-0002-4577-8276

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Finding, exploring and filtering frequent sentence-based associations between a disease and a biomedical entity, co-mentioned in disease-related PubMed literature, is a challenge, as the volume of publications increases. Darling is a web application, which utilizes Name Entity Recognition to identify human-related biomedical terms in PubMed articles, mentioned in OMIM, DisGeNET and Human Phenotype Ontology (HPO) disease records, and generates an interactive biomedical entity association network. Nodes in this network represent genes, proteins, chemicals, functions, tissues, diseases, environments and phenotypes. Users can search by identifiers, terms/entities or free text and explore the relevant abstracts in an annotated format.

Indexed as

ProteinsSoftwareData MiningPhenotypePubMedProteinsbioinformaticsdata integrationliterature-derived associationsnamed-entity recognitiontext-mining

Identifiers

PMID35454109
PMCPMC9028073

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.