Evidence map›Paper›PMID 35454092›Full record

ArticleBiomolecules2022

Plg-R

Lindsey A Miles, Stan Krajewski, Nagyung Baik, Robert J Parmer, Barbara M Mueller

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomolecules, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
3.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. A prognostic gene signature for gastric cancer and the immune infiltration-associated mechanism underlying the signature gene, PLG.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2023
    Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Lindsey A MilesDepartment of Molecular Medicine, Scripps Research Institute, La Jolla, CA 92037, USA.ORCID 0000-0002-0368-0895
Stan KrajewskiCellstan-Immunoquant Inc., Oceanside, CA 92054, USA.
Nagyung BaikDepartment of Molecular Medicine, Scripps Research Institute, La Jolla, CA 92037, USA.
Robert J ParmerDepartment of Medicine, Veterans Administration San Diego Healthcare System, University of California San Diego, San Diego, CA 92161, USA.
Barbara M MuellerSan Diego Biomedical Research Institute, San Diego, CA 92121, USA.
Scripps Research Institute · USSan Diego Biomedical Research Institute · USUniversity of California San Diego · US

Funding

Regulation of plasminogen-dependent cell functions by the novel receptor, Plg-RKTR01HL081046 · NHLBI · SCRIPPS RESEARCH INSTITUTE, THE · PI MILES, LINDSEY A · 2007 to 2024
$8.7M
Distinguishing plasminogen-dependent and plasminogen-independent roles of the plasminogen receptor, Plg-RKTR21HD101133 · NICHD · SCRIPPS RESEARCH INSTITUTE, THE · PI MILES, LINDSEY A · 2020 to 2021
$488k
NHLBI NIH HHS R01 HL081046NICHD NIH HHS R21 HD101133NIH HHS HD101133, HL 081046, CA 166473
6 · The paper itself

Abstract

The plasminogen activation system regulates the activity of the serine protease, plasmin. The role of plasminogen receptors in cancer progression is being increasingly appreciated as key players in modulation of the tumor microenvironment. The interaction of plasminogen with cells to promote plasminogen activation requires the presence of proteins exposing C-terminal lysines on the cell surface. Plg-R

Indexed as

Breast NeoplasmsReceptors, Cell SurfaceCell MembraneFemaleHumansPlasminogenSerine ProteasesTumor MicroenvironmentPlasminogenPLGRKT protein, humanReceptors, Cell SurfaceSerine Proteasesbreast cancerplasminogenPlg-RKTtissue microarraystumor microenvironment

Identifiers

PMID35454092
PMCPMC9028288
OpenAlexW4220732032

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.