Evidence map›Paper›PMID 35454040›Full record

ArticleDiagnostics (Basel, Switzerland)2022

Doppler and Spectral Ultrasound of Sacroiliac Joints in Pediatric Patients with Suspected Juvenile Spondyloarthritis.

Paolo Falsetti, Edoardo Conticini, Carla Gaggiano, Caterina Baldi, Maria Tarsia, Marco Bardelli, Stefano Gentileschi, Roberto D'Alessandro, Suhel Gabriele Al Khayyat, Alessandra Cartocci and 4 more

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Paolo FalsettiRheumatology Unit, Department of Medical Sciences, Surgery and Neurosciences, University of Siena, 53100 Siena, Italy.ORCID 0000-0003-2667-4866
Edoardo ConticiniRheumatology Unit, Department of Medical Sciences, Surgery and Neurosciences, University of Siena, 53100 Siena, Italy.ORCID 0000-0002-3974-6606
Carla GaggianoRheumatology Unit, Department of Medical Sciences, Surgery and Neurosciences, University of Siena, 53100 Siena, Italy.ORCID 0000-0003-1401-8343
Caterina BaldiRheumatology Unit, Department of Medical Sciences, Surgery and Neurosciences, University of Siena, 53100 Siena, Italy.
Maria TarsiaClinical Pediatrics Unit, Department of Molecular Medicine and Development, University of Siena, 53100 Siena, Italy.ORCID 0000-0002-1287-5854
Marco BardelliRheumatology Unit, Department of Medical Sciences, Surgery and Neurosciences, University of Siena, 53100 Siena, Italy.
Stefano GentileschiRheumatology Unit, Department of Medical Sciences, Surgery and Neurosciences, University of Siena, 53100 Siena, Italy.ORCID 0000-0001-6658-1037
Roberto D'AlessandroRheumatology Unit, Department of Medical Sciences, Surgery and Neurosciences, University of Siena, 53100 Siena, Italy.ORCID 0000-0002-8350-7581
Suhel Gabriele Al KhayyatRheumatology Unit, Department of Medical Sciences, Surgery and Neurosciences, University of Siena, 53100 Siena, Italy.
Alessandra CartocciDepartment of Medical Biotechnologies, University of Siena, 53100 Siena, Italy.
Claudia FabianiOphthalmology Unit, Department of Medical Sciences, Surgery and Neurosciences, University of Siena, 53100 Siena, Italy.
Luca CantariniRheumatology Unit, Department of Medical Sciences, Surgery and Neurosciences, University of Siena, 53100 Siena, Italy.ORCID 0000-0002-7352-1275
Maria Antonietta MazzeiUnit of Diagnostic Imaging, Department of Medical Sciences, Surgery and Neurosciences and of Radiological Sciences, University of Siena, 53100 Siena, Italy.
Bruno FredianiRheumatology Unit, Department of Medical Sciences, Surgery and Neurosciences, University of Siena, 53100 Siena, Italy.
University of Siena · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Power Doppler ultrasound (PDUS) with spectral wave analysis (SWA) has been compared with magnetic resonance imaging (MRI) in documenting active sacroiliitis in early spondyloarthritis (SpA) but, to date, PDUS/SWA has not been yet applied to the study of sacroiliac joints (SIJs) in children. Methods: A group of 20 children (13 F/7 M, mean age 14.2 y) with suspected juvenile SpA (jSpA) underwent PDUS/SWA and, subsequently, MRI of the SIJs. SIJs PDUS scoring and resistance index (RI) of the SIJs flows were recorded. The accuracy of PDUS/SWA for the diagnosis of active sacroiliitis was evaluated, with MRI as the gold standard. Results: PDUS signals were detected in 19 patients and 30 SIJs. Bone marrow edema (BME) lesions on MRI were detected in 12 patients (diagnosed as jSpA) and 22 SIJs. PDUS scoring on SIJs were higher in patients with a final diagnosis of jSpA (p = 0.003). On SWA, the mean RIs in patients with or without final diagnosis of active sacroiliitis were, respectively, 0.604 and 0.767 (p = 0.005) at joint level. A RI < 0.55 and PDUS > 1 showed the higher specificity for sacroiliitis (AUROC curve 0.854 for PDUS and 0.920 for RI). SIJs PDUS/SWA showed an overall concordance of 82.35%, with substantial agreement (k = 0.627) with MRI on the diagnosis of sacroiliitis. Conclusions: In children with sacroiliitis, PDUS demonstrates a rich vascularization into SIJs and low RIs (<0.55) have high specificity for this condition. SIJs PDUS/SWA could be useful as a screening method in children with suspected jSpA.

Indexed as

juvenile spondyloarthritismagnetic resonance imagingpediatricpower doppler ultrasoundsacroiliitis

Identifiers

PMID35454040
PMCPMC9029561
OpenAlexW4223968059

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.