ArticleDiagnostics (Basel, Switzerland)2022
Differential Vaginal Microbiota Profiling in Lactic-Acid-Producing Bacteria between Infertile Women with and without Chronic Endometritis.
Article in Diagnostics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 22 citations in OpenAlex.
- Endometrial microbiota-targeted therapies for chronic endometritis-associated recurrent implantation failure and their impact on IVF outcomes: A systematic review and methodological quality assessment.Acta obstetricia et gynecologica Scandinavica · 2026Pooled it
- Vaginal and endometrial microbiota dysbiosis in patients with chronic endometritis: a systematic review and meta-analysis.Frontiers in cellular and infection microbiology · 2026Pooled it
- Multi-drug-resistant chronic endometritis in infertile women with repeated implantation failure: trend over the decade and pilot study for third-line oral antibiotic treatment.Journal of assisted reproduction and genetics · 2022Trial
- Endometriosis and Chronic Endometritis: Shared Mechanisms, Diagnostic Challenges, and Clinical Implications in Infertility.Diagnostics (Basel, Switzerland) · 2026Review
- Endometrial microbiota-dimethylglycine-Treg cell axis affects endometrial receptivity in recurrent implantation failure.Science China. Life sciences · 2026Article
- Chronic endometritis diagnosis and fertility outcomes: an old unresolved question.Reproduction & fertility · 2025Article
- Vaginal microbiome and recurrent pregnancy loss.Infection and immunity · 2025Review
- Behind-the-Scenes Actors in Fertility: A Comprehensive Review of the Female Reproductive Tract Microbiome and Its Clinical Relevance.Life (Basel, Switzerland) · 2025Review
- All Properties of Infertility Microbiome in a Review Article.Journal of clinical laboratory analysis · 2025Review
- Microbiota and Recurrent Pregnancy Loss (RPL); More than a Simple Connection.Microorganisms · 2024Review
- Antibiotics combined with vaginal probiotics in the embryo transfer cycle of infertile patients with chronic endometritis.Frontiers in cellular and infection microbiology · 2024Article
- Diagnostic factors for recurrent pregnancy loss: an expanded workup.Archives of gynecology and obstetrics · 2023Article
- The Interplay betweenMicroorganisms · 2023Review
- Challenges in Clinical Diagnosis and Management of Chronic Endometritis.Diagnostics (Basel, Switzerland) · 2022Review
- Genital tract dysbiosis in infertile women with a history of repeated implantation failure and pilot study for reproductive outcomes following oral enteric coating lactoferrin supplementation.Archives of gynecology and obstetrics · 2022Article
- Diagnosing chronic endometritis: when simplification fails to clarify.Human reproduction open · 2022Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeChronic endometritis (CE) is an infectious and inflammatory disorder associated with infertility of unknown etiology, repeated implantation failure, and recurrent pregnancy loss. In the current clinical practice, intrauterine interventions such as endometrial biopsy/histopathologic examinations and/or hysteroscopy are required for the diagnosis of CE. In this study, we analyzed the microbiota in vaginal secretions (VS) as a potential prediction tool for CE in infertile women.
methodsUsing next-generation sequencing analysis, we compared the VS and endometrial fluid (EF) microbiota in infertile women with (
resultsThe detection rate of
conclusionThese findings suggest that VS microbiota in infertile women with CE is characterized by the reduction in TRIAL REGISTRATION NUMBER: UMIN000029449 (registration date 6 October 2017).
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.