Evidence map›Paper›PMID 35453830›Full record

ArticleDiagnostics (Basel, Switzerland)2022

Reduction of Peristalsis-Related Streak Artifacts on the Liver with Dual-Layer Spectral CT.

Sergio Grosu, Zhen J Wang, Markus M Obmann, Mark D Sugi, Yuxin Sun, Benjamin M Yeh

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 3 countries.

Sergio GrosuDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, 513 Parnassus Ave., San Francisco, CA 94143, USA.ORCID 0000-0002-9093-6499
Zhen J WangDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, 513 Parnassus Ave., San Francisco, CA 94143, USA.
Markus M ObmannDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, 513 Parnassus Ave., San Francisco, CA 94143, USA.
Mark D SugiDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, 513 Parnassus Ave., San Francisco, CA 94143, USA.ORCID 0000-0002-2154-3990
Yuxin SunDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, 513 Parnassus Ave., San Francisco, CA 94143, USA.
Benjamin M YehDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, 513 Parnassus Ave., San Francisco, CA 94143, USA.
University of California, San Francisco · US

Funding

Nanoparticle CT Contrast Agent for New Capabilities in Tumor Detection, Staging, and Therapy Planning and ResponseR01CA226868 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI YEH, BENJAMIN M · 2019 to 2022
$3.1M
NCI NIH HHS R01 CA226868NIH HHS R01CA226868Philips (United States) n/a
6 · The paper itself

Abstract

Background: Peristalsis-related streak artifacts on the liver compromise image quality and diagnostic accuracy. Purpose: To assess dual-layer spectral-detector computed tomography (CT) image reconstructions for reducing intestinal peristalsis-related streak artifacts on the liver. Methods: We retrospectively evaluated 220 contrast-enhanced abdominal dual-energy CT scans in 131 consecutive patients (mean age: 68 ± 10 years, 120 men) who underwent routine clinical dual-layer spectral-detector CT imaging (120 kVp, 40 keV, 200 keV, virtual non-contrast (VNC), iodine images). Two independent readers evaluated bowel peristalsis streak artifacts on the liver qualitatively on a five-point Likert scale (1 = none to 5 = severe) and quantitatively by depth of streak artifact extension into the liver and measurements of Hounsfield Unit and iodine concentration differences from normal liver. Artifact severity between image reconstructions were compared by Wilcoxon signed-rank and paired t-tests. Results: 12 scans were excluded due to missing spectral data, artifacts on the liver originating from metallic foreign materials, or oral contrast material. Streak artifacts on the liver were seen in 51/208 (25%) scans and involved the left lobe only in 49/51 (96%), the right lobe only in 0/51 (0%), and both lobes in 2/51 (4%) scans. Artifact frequency was lower in iodine than in 120 kVp images (scans 18/208 vs. 51/208, p < 0.001). Artifact severity was less in iodine than in 120 kVp images (median score 1 vs. 3, p < 0.001). Streak artifact extension into the liver was shorter in iodine than 120 kVp images (mean length 2 ± 4 vs. 12 ± 5 mm, p < 0.001). Hounsfield Unit and iodine concentration differed significantly between bright streak artifacts and normal liver in 120 kVp, 40 keV, 200 keV, and VNC images (p < 0.001, each), but not in iodine images (p = 0.23). Conclusion: Intestinal peristalsis-related streak artifacts commonly affect the left liver lobe at CT and can be substantially reduced by viewing iodine dual-energy CT image reconstructions.

Indexed as

abdomenartifactsDECThumansliverperistalsistomographyX-ray computed

Identifiers

PMID35453830
PMCPMC9028529
OpenAlexW4224322154

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.