Evidence map›Paper›PMID 35453812›Full record

ArticleBiology2022

Kinetic Alterations in Resurgent Sodium Currents of Mutant Na

Ming-Jen Lee, Pi-Chen Lin, Ming-Hong Lin, Hsin-Ying Clair Chiou, Kai Wang, Chiung-Wei Huang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Ming-Jen LeeDepartment of Neurology, National Taiwan University Hospital, Taipei 100, Taiwan.
Pi-Chen LinDivision of Endocrinology and Metabolism, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung 80756, Taiwan.
Ming-Hong LinDepartment of Microbiology and Immunology, School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 807, Taiwan.ORCID 0000-0003-2637-066X
Hsin-Ying Clair ChiouCenter of Teaching and Research, Kaohsiung Municipal Siaogang Hospital, Kaohsiung Medical University, Kaohsiung 807, Taiwan.
Kai WangInstitute for Systems Biology, Seattle, WA 98109, USA.
Chiung-Wei HuangDepartment of Post Baccalaureate Medicine, Kaohsiung Medical University, Kaohsiung 807, Taiwan.
Kaohsiung Medical University · TWInstitute for Systems Biology · USNational Taiwan University Hospital · TW

Funding

Kaohsiung Medical Univerity Hospital KMUH106-M608Kaohsiung Medical University KMU-Q107007Kaohsiung Medical Univetsity KMU-Q108004Ministry of Science and Technology Taiwan 107-2320-B-037-004Ministry of Science and Technology Taiwan 109-2314-B-002-121-MY3Ministry of Science and Technology Taiwan 109-2320-B-037-009Ministry of Science and Technology Taiwan 110-2320-B-037-004
6 · The paper itself

Abstract

Paramyotonia congenita (PMC) is a rare skeletal muscle disorder characterized by muscle stiffness upon repetitive exercise and cold exposure. PMC was reported to be caused by dominant mutations in the SCN4A gene encoding the α subunit of the Na

Indexed as

Nav1.4 channelparamyotonia congenitaresurgent currents

Identifiers

PMID35453812
PMCPMC9031228
OpenAlexW4224281302

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.