Evidence map›Paper›PMID 35453788›Full record

ArticleBiology2022

RNA-seq and Mitochondrial DNA Analysis of Adrenal Gland Metastatic Tissue in a Patient with Renal Cell Carcinoma.

Tomoyoshi Komiyama, Hakushi Kim, Masayuki Tanaka, Sanae Isaki, Keiko Yokoyama, Akira Miyajima, Hiroyuki Kobayashi

Erratum issuedOpen access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Tomoyoshi KomiyamaDepartment of Clinical Pharmacology, Tokai University School of Medicine, Kanagawa, Isehara 259-1193, Japan.ORCID 0000-0003-2138-0084
Hakushi KimDepartment of Urology, Tokai University Hachioji Hospital, Tokyo 192-0032, Japan.ORCID 0000-0001-8225-2874
Masayuki TanakaMedical Science College Office, Tokai University, Isehara 259-1193, Kanagawa, JapanORCID 0000-0002-8682-8719
Sanae IsakiMedical Science College Office, Tokai University, Isehara 259-1193, Kanagawa, Japan
Keiko YokoyamaMedical Science College Office, Tokai University, Isehara 259-1193, Kanagawa, Japan
Akira MiyajimaDepartment of Urology, Tokai University School of Medicine, Isehara 259-1193, Kanagawa, Japan
Hiroyuki KobayashiDepartment of Clinical Pharmacology, Tokai University School of Medicine, Kanagawa, Isehara 259-1193, Japan.
Tokai University · JPTokai University Hachioji Hospital · JP

Funding

Grants-in-Aid for Scientific Research 18K09180
6 · The paper itself

Abstract

This study aimed to clarify whether genetic mutations participate in renal cell carcinoma (RCC) metastasis to the adrenal gland (AG). Our study analyzed whole mitochondrial gene and ribonucleic acid sequencing (RNA-seq) data from a male patient in his 60s with metastatic RCC. We confirmed common mutation sites in the mitochondrial gene and carried out Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis using RNA-seq data for RCC and adrenal carcinoma. Furthermore, we confirmed the common mutation sites of mitochondrial genes in which the T3394Y (p.H30Y) site transitioned from histidine (His.; H) to tyrosine (Tyr.; Y) in the NADH dehydrogenase subunit 1 (

Indexed as

adrenal glandmetastasisrenal cell carcinomaRNA-seqwhole mtDNA region

Identifiers

PMID35453788
PMCPMC9030821
OpenAlexW4224118768

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.