Evidence map›Paper›PMID 35453743›Full record

ArticleBiology2022

Number of Teeth Is Related to Craniofacial Morphology in Humans.

Elias S Oeschger, Georgios Kanavakis, Alina Cocos, Demetrios J Halazonetis, Nikolaos Gkantidis

Open access · goldAbstract read
In one paragraph

Article in Biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Comment on "Association between tooth agenesis and root morphology assessed by periapical radiographs".Journal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 3 countries.

Elias S OeschgerDepartment of Orthodontics and Dentofacial Orthopedics, University of Bern, CH-3010 Bern, Switzerland.ORCID 0000-0001-7949-8785
Georgios KanavakisDepartment of Orthodontics and Pediatric Dentistry, UZB-University School of Dental Medicine, University of Basel, CH-4056 Basel, Switzerland.ORCID 0000-0001-7304-044X
Alina CocosDepartment of Orthodontics, School of Dentistry, National and Kapodistrian University of Athens, GR-11527 Athens, Greece.
Demetrios J HalazonetisDepartment of Orthodontics, School of Dentistry, National and Kapodistrian University of Athens, GR-11527 Athens, Greece.ORCID 0000-0002-6501-8709
Nikolaos GkantidisDepartment of Orthodontics and Dentofacial Orthopedics, University of Bern, CH-3010 Bern, Switzerland.ORCID 0000-0002-3180-6272
National and Kapodistrian University of Athens · GRUniversity of Bern · CHTufts University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

One of the most common dental anomalies in humans is the congenital absence of teeth, referred to as tooth agenesis. The association of tooth agenesis to craniofacial morphology has been previously investigated but remains unclear. We investigated this association by applying geometric morphometric methods in a large sample of modern humans. In line with previous studies, we report here that a reduced teeth number is linked to a less convex profile, as well as to a shorter face. The effects were similar for males and females; they increased as the severity of the tooth agenesis increased and remained unaltered by the inclusion of third molars and of allometry in the analysis. Furthermore, in cases with tooth agenesis only in the maxilla, there was no detectable effect in mandibular shape, whereas maxillary shape was affected independently of the location of missing teeth. The robustness of the present sample along with the shape analysis and the statistical approach applied, allowed for thorough testing of various contributing factors regarding the presence but also the magnitude of effects. The present findings suggest a relationship between number of teeth and overall craniofacial development and have evolutionary implications.

Indexed as

growth/developmenthypodontiamorphogenesismorphometricsoligodontiatooth agenesistooth development

Identifiers

PMID35453743
PMCPMC9029740
OpenAlexW4224307791

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.