Evidence map›Paper›PMID 35453681›Full record

ArticleBiology2022

Integrated In Silico Analyses Identify PUF60 and SF3A3 as New Spliceosome-Related Breast Cancer RNA-Binding Proteins.

Jennyfer M García-Cárdenas, Isaac Armendáriz-Castillo, Andy Pérez-Villa, Alberto Indacochea, Andrea Jácome-Alvarado, Andrés López-Cortés, Santiago Guerrero

Open access · goldAbstract read
In one paragraph

Article in Biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.6field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. International journal of molecular sciences · 2026
    Review
  4. Review
  5. Article
  6. RNA binding proteins in cardiovascular development and disease.Current topics in developmental biology · 2024
    Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 2 countries.

Jennyfer M García-CárdenasEscuela de Medicina, Facultad de Ciencias Médicas de la Salud y de la Vida, Universidad Internacional del Ecuador, Quito 170113, Ecuador.ORCID 0000-0001-9035-7668
Isaac Armendáriz-CastilloLatin American Network for the Implementation and Validation of Clinical Pharmacogenomics Guidelines (RELIVAF-CYTED), 28001 Madrid, Spain.ORCID 0000-0003-2636-2707
Andy Pérez-VillaLatin American Network for the Implementation and Validation of Clinical Pharmacogenomics Guidelines (RELIVAF-CYTED), 28001 Madrid, Spain.
Alberto IndacocheaCentre for Genomic Regulation (CRG), Barcelona Institute of Science and Technology, 08003 Barcelona, Spain.ORCID 0000-0003-2643-9807
Andrea Jácome-AlvaradoEscuela de Medicina, Facultad de Ciencias Médicas de la Salud y de la Vida, Universidad Internacional del Ecuador, Quito 170113, Ecuador.
Andrés López-CortésLatin American Network for the Implementation and Validation of Clinical Pharmacogenomics Guidelines (RELIVAF-CYTED), 28001 Madrid, Spain.ORCID 0000-0003-1503-1929
Santiago GuerreroEscuela de Medicina, Facultad de Ciencias Médicas de la Salud y de la Vida, Universidad Internacional del Ecuador, Quito 170113, Ecuador.ORCID 0000-0003-3473-7214
Universidade da Coruña · ESCentre for Genomic Regulation · ESInstituto Nacional de Investigación en Salud Pública · ECUniversidad de Las Américas · ECUniversidad Internacional del Ecuador · EC

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

More women are diagnosed with breast cancer (BC) than any other type of cancer. Although large-scale efforts have completely redefined cancer, a cure remains unattainable. In that respect, new molecular functions of the cell should be investigated, such as post-transcriptional regulation. RNA-binding proteins (RBPs) are emerging as critical post-transcriptional modulators of tumorigenesis, but only a few have clear roles in BC. To recognize new putative breast cancer RNA-binding proteins, we performed integrated in silico analyses of all human RBPs (

Indexed as

breast cancercancer driver genesin silico analysisRBPs

Identifiers

PMID35453681
PMCPMC9030152
OpenAlexW4221033270

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.