Evidence map›Paper›PMID 35453524›Full record

ReviewBiomedicines2022

Autoimmune Encephalitis in COVID-19 Infection: Our Experience and Systematic Review of the Literature.

Adina Stoian, Mircea Stoian, Zoltan Bajko, Smaranda Maier, Sebastian Andone, Roxana Adriana Cioflinc, Anca Motataianu, Laura Barcutean, Rodica Balasa

Open access · goldAbstract readReview
In one paragraph

Review in Biomedicines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Adina StoianDepartment of Pathophysiology, George Emil Palade University of Medicine, Pharmacy, Sciences and Technology Targu Mures, 540136 Targu Mures, Romania.ORCID 0000-0001-6862-4926
Mircea StoianDepartment of Anesthesiology and Critical Care Medicine, George Emil Palade University of Medicine, Pharmacy, Sciences and Technology Targu Mures, 540136 Targu Mures, Romania.
Zoltan BajkoIst Neurology Clinic, Mures County Clinical Emergency Hospital, 540136 Targu Mures, Romania.ORCID 0000-0001-7379-4743
Smaranda MaierIst Neurology Clinic, Mures County Clinical Emergency Hospital, 540136 Targu Mures, Romania.
Sebastian AndoneIst Neurology Clinic, Mures County Clinical Emergency Hospital, 540136 Targu Mures, Romania.
Roxana Adriana CioflincIst Neurology Clinic, Mures County Clinical Emergency Hospital, 540136 Targu Mures, Romania.
Anca MotataianuIst Neurology Clinic, Mures County Clinical Emergency Hospital, 540136 Targu Mures, Romania.
Laura BarcuteanIst Neurology Clinic, Mures County Clinical Emergency Hospital, 540136 Targu Mures, Romania.ORCID 0000-0002-3033-0583
Rodica BalasaIst Neurology Clinic, Mures County Clinical Emergency Hospital, 540136 Targu Mures, Romania.
Universitatea de Medicină, Farmacie, Științe și Tehnologie „George Emil Palade” din Târgu Mureș · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The neurologic complications of COVID-19 infection are frequent in hospitalized patients; a high percentage of them present neurologic manifestations at some point during the course of their disease. Headache, muscle pain, encephalopathy and dizziness are among the most common complications. Encephalitis is an inflammatory condition with many etiologies. There are several forms of encephalitis associated with antibodies against intracellular neuronal proteins, cell surfaces or synaptic proteins, referred to as autoimmune encephalitis. Several case reports published in the literature document autoimmune encephalitis cases triggered by COVID-19 infection. Our paper first presents our experience in this issue and then systematically reviews the literature on autoimmune encephalitis that developed in the background of SARS-CoV-2 infections and also discusses the possible pathophysiological mechanisms of auto-immune-mediated damage to the nervous system. This review contributes to improve the management and prognosis of COVID-19-related autoimmune encephalitis.

Indexed as

autoimmune encephalitisCOVID-19 infectionvoltage-gated potassium channels antibody

Identifiers

PMID35453524
PMCPMC9024859
OpenAlexW4221053071

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.