Evidence map›Paper›PMID 35453490›Full record

ArticleBiomedicines2022

Preclinical Development of Bioengineered Allografts Derived from Decellularized Human Diaphragm.

Silvia Barbon, Elena Stocco, Martina Contran, Federico Facchin, Rafael Boscolo-Berto, Silvia Todros, Deborah Sandrin, Filippo Romanato, Piero Pavan, Veronica Macchi and 4 more

Open access · goldAbstract read
In one paragraph

Article in Biomedicines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
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  5. Article
  6. Review
  7. Article
  8. Article
  9. From waste to wealth: Repurposing slaughterhouse waste for xenotransplantation.Frontiers in bioengineering and biotechnology · 2023
    Article
  10. Article
  11. Article
  12. Review
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Silvia BarbonSection of Human Anatomy, Department of Neuroscience, University of Padova, 35121 Padova, Italy.ORCID 0000-0003-2435-0753
Elena StoccoSection of Human Anatomy, Department of Neuroscience, University of Padova, 35121 Padova, Italy.
Martina ContranSection of Human Anatomy, Department of Neuroscience, University of Padova, 35121 Padova, Italy.
Federico FacchinLife Lab Program, Consorzio per la Ricerca Sanitaria, 35121 Padova, Italy.ORCID 0000-0002-6695-1103
Rafael Boscolo-BertoSection of Human Anatomy, Department of Neuroscience, University of Padova, 35121 Padova, Italy.
Silvia TodrosDepartment of Industrial Engineering, Centre for Mechanics of Biological Materials, University of Padova, Via Venezia 1, 35131 Padova, Italy.ORCID 0000-0002-6077-9672
Deborah SandrinLife Lab Program, Consorzio per la Ricerca Sanitaria, 35121 Padova, Italy.
Filippo RomanatoLife Lab Program, Consorzio per la Ricerca Sanitaria, 35121 Padova, Italy.ORCID 0000-0003-0243-1464
Piero PavanDepartment of Industrial Engineering, Centre for Mechanics of Biological Materials, University of Padova, Via Venezia 1, 35131 Padova, Italy.
Veronica MacchiSection of Human Anatomy, Department of Neuroscience, University of Padova, 35121 Padova, Italy.ORCID 0000-0003-2335-6897
Vincenzo VindigniLife Lab Program, Consorzio per la Ricerca Sanitaria, 35121 Padova, Italy.ORCID 0000-0001-6638-9010
Franco BassettoLife Lab Program, Consorzio per la Ricerca Sanitaria, 35121 Padova, Italy.
Raffaele De CaroSection of Human Anatomy, Department of Neuroscience, University of Padova, 35121 Padova, Italy.ORCID 0000-0002-2307-0277
Andrea PorzionatoSection of Human Anatomy, Department of Neuroscience, University of Padova, 35121 Padova, Italy.
University of Padua · IT

Funding

'Consorzio per la Ricerca Sanitaria' (CORIS) of the Veneto Region, Italy (L.i.f.e.L.a.b. Program) DGR1017, July 17, 2018
6 · The paper itself

Abstract

Volumetric muscle loss (VML) is the traumatic/surgical loss of skeletal muscle, causing aesthetic damage and functional impairment. Suboptimal current surgical treatments are driving research towards the development of optimised regenerative therapies. The grafting of bioengineered scaffolds derived from decellularized skeletal muscle may be a valid option to promote structural and functional healing. In this work, a cellular human diaphragm was considered as a scaffold material for VML treatment. Decellularization occurred through four detergent-enzymatic protocols involving (1) sodium dodecyl sulfate (SDS), (2) SDS + Tergitol

Indexed as

decellularizationextracellular matrixhuman diaphragmskeletal muscletissue engineering

Identifiers

PMID35453490
PMCPMC9031975
OpenAlexW4220913190

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.