Evidence map›Paper›PMID 35453449›Full record

ArticleAntioxidants (Basel, Switzerland)2022

An ACE2-Alamandine Axis Modulates the Cardiac Performance of the Goldfish

Mariacristina Filice, Rosa Mazza, Sandra Imbrogno, Olga Mileti, Noemi Baldino, Amilcare Barca, Gianmarco Del Vecchio, Tiziano Verri, Alfonsina Gattuso, Maria Carmela Cerra

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Mariacristina FiliceDepartment of Biology, Ecology and Earth Sciences, University of Calabria, Arcavacata, 87036 Rende, Italy.ORCID 0000-0002-1218-0358
Rosa MazzaDepartment of Biology, Ecology and Earth Sciences, University of Calabria, Arcavacata, 87036 Rende, Italy.
Sandra ImbrognoDepartment of Biology, Ecology and Earth Sciences, University of Calabria, Arcavacata, 87036 Rende, Italy.ORCID 0000-0002-3389-4085
Olga MiletiDepartment of Information, Modeling, Electronics and System Engineering, University of Calabria, Arcavacata, 87036 Rende, Italy.
Noemi BaldinoDepartment of Information, Modeling, Electronics and System Engineering, University of Calabria, Arcavacata, 87036 Rende, Italy.ORCID 0000-0002-0064-5103
Amilcare BarcaDepartment of Biological and Environmental Sciences and Technologies, University of Salento, 73100 Lecce, Italy.ORCID 0000-0002-3117-2724
Gianmarco Del VecchioDepartment of Biological and Environmental Sciences and Technologies, University of Salento, 73100 Lecce, Italy.
Tiziano VerriDepartment of Biological and Environmental Sciences and Technologies, University of Salento, 73100 Lecce, Italy.ORCID 0000-0003-4983-2767
Alfonsina GattusoDepartment of Biology, Ecology and Earth Sciences, University of Calabria, Arcavacata, 87036 Rende, Italy.ORCID 0000-0002-4908-0633
Maria Carmela CerraDepartment of Biology, Ecology and Earth Sciences, University of Calabria, Arcavacata, 87036 Rende, Italy.
University of Calabria · ITUniversity of Salento · IT

Funding

Ministry of Education, Universities and Research ex 60%Ministry of Education, Universities and Research PON "Ricerca e Innovazione" 2014-2020, Asse IV "Istruzione e ricerca per il recupero", Azione IV.6 -"Contratti di ricerca su tematiche Green" (D.M. 1062 del 10.08.2021)
6 · The paper itself

Abstract

Alamandine is a peptide of the Renin Angiotensin System (RAS), either generated from Angiotensin A via the Angiotensin Converting Enzyme 2 (ACE2), or directly from Ang-(1-7). In mammals, it elicits cardioprotection via Mas-related G-protein-coupled receptor D (MrgD), and the NOS/NO system. In teleost fish, RAS is known to modulate heart performance. However, no information is available on the presence of a cardioactive ACE2/Alamandine axis. To fill this gap, we used the cyprinid teleost

Indexed as

ACE2almandineCarassius auratusheartNOS/NO systemteleost

Identifiers

PMID35453449
PMCPMC9026556
OpenAlexW4223454132

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.