Evidence map›Paper›PMID 35453445›Full record

ArticleAntioxidants (Basel, Switzerland)2022

NRF2 Alters Mitochondrial Gene Expression in Neonate Mice Exposed to Hyperoxia.

Heather L Vellers, Hye-Youn Cho, Wesley Gladwell, Kevin Gerrish, Janine H Santos, Gaston Ofman, Laura Miller-DeGraff, T Beth Mahler, Steven R Kleeberger

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Heather L VellersHealth and Exercise Science Department, University of Oklahoma, Norman, OK 73019, USA.ORCID 0000-0001-8936-9936
Hye-Youn ChoImmunity, Inflammation, and Disease Laboratory, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA.ORCID 0000-0002-8671-8544
Wesley GladwellMolecular Genomics Core Laboratory, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA.
Kevin GerrishMolecular Genomics Core Laboratory, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA.
Janine H SantosDivision of the National Toxicology Program, Mechanistic Toxicology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA.ORCID 0000-0001-6384-3070
Gaston OfmanDepartment of Pediatrics, The University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.ORCID 0000-0002-1087-0187
Laura Miller-DeGraffImmunity, Inflammation, and Disease Laboratory, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA.
T Beth MahlerDivision of the National Toxicology Program, Comparative and Molecular Pathogenesis Branch, Research Triangle Park, NC 27709, USA.
Steven R KleebergerImmunity, Inflammation, and Disease Laboratory, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA.
National Institute of Environmental Health Sciences · USResearch Triangle Park Foundation · USUniversity of Oklahoma · USUniversity of Oklahoma Health Sciences Center · US

Funding

Molecular Genetics Support to Identify Gene/Environment Interactions in DiseaseZICES102546 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI GERRISH, KEVIN · 2009 to 2025
$30.5M
Consumer Products and Therapeutics Research ProgramZIAES103379 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI TAYLOR, KYLA · 2022 to 2025
$9.9M
6 · The paper itself

Abstract

Approximately 1 in 10 newborns are born preterm and require supplemental oxygen (O

Indexed as

DNA lesionsheteroplasmymitochondrial functionmitochondrial sequencingmtDNA copy numberNRF2

Identifiers

PMID35453445
PMCPMC9031618
OpenAlexW4223592224

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.