Evidence map›Paper›PMID 35453335›Full record

ArticleAntioxidants (Basel, Switzerland)2022

Preparation, Characterization, and Antioxidant Activity of Nanoemulsions Incorporating Lemon Essential Oil.

Ting Liu, Zhipeng Gao, Weiming Zhong, Fuhua Fu, Gaoyang Li, Jiajing Guo, Yang Shan

Abstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Article
  2. Article
  3. Effect ofFood science & nutrition · 2026
    Article
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  7. Article
  8. Article
  9. Article
  10. Review
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  12. Article
  13. Article
  14. Article
  15. Green Synthesis ofMolecules (Basel, Switzerland) · 2024
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ting LiuLongping Branch, Graduate School of Hunan University, Changsha 410125, China.
Zhipeng GaoCollege of Animal Science and Technology, Hunan Agricultural University, Changsha 410128, China.
Weiming ZhongCollege of Animal Science and Technology, Hunan Agricultural University, Changsha 410128, China.
Fuhua FuLongping Branch, Graduate School of Hunan University, Changsha 410125, China.
Gaoyang LiLongping Branch, Graduate School of Hunan University, Changsha 410125, China.
Jiajing GuoLongping Branch, Graduate School of Hunan University, Changsha 410125, China.
Yang ShanLongping Branch, Graduate School of Hunan University, Changsha 410125, China.

Funding

Changsha Municipal Natural Science Foundation kq2202332, kq2014070Hunan Academy of Agricultural Sciences 2020CX47Hunan Academy of Agricultural Sciences 2021CX05Hunan Provincial Science and Technology Department 2019NK2041Ministry of Agriculture and Rural Affairs S2021KFKT-22National Natural Science Foundation of China 32073020
6 · The paper itself

Abstract

Lemon essential oil (LEO) is a kind of citrus essential oil with antioxidant, anti-inflammatory, and antimicrobial activities, but low water solubility and biological instability hinder its industrial application. In this study, LEO was nanoemulsified to solve these problems. The preparation procedure of lemon essential oil nanoemulsions (LEO-NEs) was optimized, and the physicochemical characterization and antioxidant activities were explored. Single-factor experiments (SFEs) and response surface methodology (RSM) were conducted for the effects on the mean droplet size of LEO-NEs. Five factors of SFE which may influence the droplet size were identified: HLB value, concentration of essential oil, concentration of surfactant, ultrasonic power, and ultrasonic time. On the basis of the SFE, the RSM approach was used to optimize the preparation procedure to obtain LEO-NEs with the smallest droplet size. LEO-NEs exhibited good antioxidant activity when the HLB value was 13, content of surfactant was 0.157 g/mL, ultrasonic time was 23.50 min, and ultrasonic power was 761.65 W. In conclusion, these results can provide a good theoretical basis for the industrial application of lemon essential oil.

Indexed as

antioxidant activitieslemon essential oilnanoemulsionsresponse surface methodologyultrasonication

Identifiers

PMID35453335
PMCPMC9025020

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.