Evidence map›Paper›PMID 35453257›Full record

ArticleAntibiotics (Basel, Switzerland)2022

Surgical Antimicrobial Prophylaxis in Pediatric Patients Undergoing Plastic Surgery: A RAND/UCLA Appropriateness Method Consensus Study.

Susanna Esposito, Rossella Sgarzani, Sonia Bianchini, Sara Monaco, Laura Nicoletti, Erika Rigotti, Marilia Di Pietro, Roberta Opri, Caterina Caminiti, Matilde Ciccia and 16 more

Open access · goldAbstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors at 15 institutions in 1 country.

Susanna EspositoPediatric Clinic, University Hospital, Department of Medicine and Surgery, University of Parma, 43126 Parma, Italy.
Rossella SgarzaniServizio di Chirurgia Plastica, Centro Grandi Ustionati, Ospedale M. Bufalini, AUSL Romagna, 47521 Cesena, Italy.
Sonia BianchiniPediatric Clinic, University Hospital, Department of Medicine and Surgery, University of Parma, 43126 Parma, Italy.
Sara MonacoPediatric Clinic, University Hospital, Department of Medicine and Surgery, University of Parma, 43126 Parma, Italy.
Laura NicolettiPediatric Clinic, University Hospital, Department of Medicine and Surgery, University of Parma, 43126 Parma, Italy.
Erika RigottiPediatric Clinic, Azienda Ospedaliera Universitaria Integrata, 37134 Verona, Italy.
Marilia Di PietroPediatric Clinic, Azienda Ospedaliera Universitaria Integrata, 37134 Verona, Italy.
Roberta OpriPediatric Clinic, Azienda Ospedaliera Universitaria Integrata, 37134 Verona, Italy.ORCID 0000-0001-5660-3992
Caterina CaminitiResearch and Innovation Unit, University Hospital of Parma, 43126 Parma, Italy.ORCID 0000-0002-3196-2435
Matilde CicciaNeonatology and Neonatal Intensive Care Unit, Ospedale Maggiore, 40133 Bologna, Italy.
Giorgio ContiPediatric ICU and Trauma Center, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00165 Rome, Italy.
Daniele DonàDivision of Paediatric Infectious Diseases, Department for Woman and Child Health, University of Padua, 35100 Padua, Italy.
Mario GiuffréDepartment of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties "G. D'Alessandro", University of Palermo, 90141 Palermo, Italy.ORCID 0000-0001-9576-1635
Stefania La GruttaInstitute of Translational Pharmacology IFT, National Research Council, 90146 Palermo, Italy.
Laura LancellaPaediatric and Infectious Disease Unit, Academic Department of Pediatrics, IRCCS Bambino Gesù Children's Hospital, 00165 Rome, Italy.
Mario LimaPediatric Surgery, IRCCS Azienda Ospedaliera-Universitaria di Bologna, 40138 Bologna, Italy.ORCID 0000-0002-5877-440X
Andrea Lo VecchioDepartment of Translational Medical Science, Section of Pediatrics, University of Naples "Federico II", 80138 Naples, Italy.ORCID 0000-0003-4181-6842
Gloria PelizzoPediatric Surgery Department, "Vittore Buzzi" Children's Hospital, 20154 Milano, Italy.
Giorgio PiacentiniPediatric Clinic, Azienda Ospedaliera Universitaria Integrata, 37134 Verona, Italy.
Carlo PietrasantaNeonatal Intensive Care Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Department of Mother, Child and Infant, 20122 Milan, Italy.ORCID 0000-0002-1019-4422
Matteo PuntoniResearch and Innovation Unit, University Hospital of Parma, 43126 Parma, Italy.ORCID 0000-0002-7908-0626
Alessandro SimoniniPediatric Anesthesia and Intensive Care Unit, Salesi Children's Hospital, 60123 Ancona, Italy.ORCID 0000-0003-3788-7672
Elisabetta VenturiniPediatric Infectious Disease Unit, Meyer's Children Hospital, 50139 Florence, Italy.ORCID 0000-0002-0048-3933
Annamaria StaianoDepartment of Translational Medical Science, Section of Pediatrics, University of Naples "Federico II", 80138 Naples, Italy.
Nicola PrincipiUniversità degli Studi di Milano, 20122 Milan, Italy.ORCID 0000-0002-3468-5568
On Behalf Of The Peri-Operative Prophylaxis In Neonatal And Paediatric Age Pop-NeoPed Study Group
University of Parma · ITAzienda Ospedaliera Universitaria Integrata Verona · ITFondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico · ITUniversity of Naples Federico II · ITAgostino Gemelli University Polyclinic · ITAzienda USL di Bologna · ITBambino Gesù Children's Hospital · ITFondazione Ospedale Salesi · ITIstituto di Farmacologia Traslazionale · ITMeyer Children's Hospital · ITOspedale dei Bambini Vittore Buzzi · ITOspedale “M. Bufalini” di Cesena · ITUniversity of Milan · ITUniversity of Padua · ITUniversity of Palermo · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

For many years, it was clearly shown that surgical procedures might be associated with surgical site infection (SSI). Many scientific institutions prepared guidelines to use in surgery to reduce abuse and misuse of antibiotics. However, in the general guidelines for surgical antibiotic prophylaxis, plastic surgical procedures are not addressed or are only marginally discussed, and children were almost systematically excluded. The main aim of this Consensus document is to provide clinicians with recommendations on antimicrobial prophylaxis for pediatric patients undergoing plastic surgery. The following scenarios were considered: clean plastic surgery in elective procedures with an exclusive skin and subcutis involvement; clean-contaminated/contaminated plastic surgery in elective procedures with an exclusive skin and subcutis involvement; elective plastic surgery with use of local flaps; elective plastic surgery with the use of grafts; prolonged elective plastic surgery; acute burns; clean contused lacerated wounds without bone exposure; high-risk contused lacerated wounds or with bone exposure; contused lacerated wound involving the oral mucosa; plastic surgery following human bite; plastic surgery following animal bite; plastic surgery with tissue expander insertion. Our Consensus document shows that antimicrobial perioperative prophylaxis in pediatric patients undergoing plastic surgery is recommended in selected cases. While waiting the results of further pediatric studies, the application of uniform and shared protocols in these procedures will improve surgical practice, with a reduction in SSIs and consequent rationalization of resources and costs, as well as limiting the phenomenon of antimicrobial resistance.

Indexed as

antibioticsburnpediatric infectious diseasesplastic surgerysurgical antibiotic prophylaxiswound

Identifiers

PMID35453257
PMCPMC9029976
OpenAlexW4223634533

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.