Evidence map›Paper›PMID 35453254›Full record

ArticleAntibiotics (Basel, Switzerland)2022

TEM,CTX-M,SHV Genes in ESBL-Producing

Alice Elena Ghenea, Ovidiu Mircea Zlatian, Oana Mariana Cristea, Anca Ungureanu, Radu Razvan Mititelu, Andrei Theodor Balasoiu, Corina Maria Vasile, Alex-Ioan Salan, Daniel Iliuta, Mihaela Popescu and 2 more

Open access · goldAbstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 1 pooled it
3.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 1 synthesis or guideline pooled it, 58 citations in OpenAlex.

  1. Pooled it
  2. Imipenem resistance inNew microbes and new infections · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Article
  14. Article
  15. Emergence of Carbapenem-ResistantPathogens (Basel, Switzerland) · 2025
    Article
  16. Article
  17. Evolutionary relationships and genetic diversity in theBiochemistry and biophysics reports · 2025
    Article
  18. Prevalence of ESBL-producingOne health (Amsterdam, Netherlands) · 2025
    Review
  19. Environmental Exposures and the Human Gut Resistome in Northwest Ecuador.medRxiv : the preprint server for health sciences · 2025
    Article
  20. CombatingFrontiers in cellular and infection microbiology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Alice Elena GheneaDepartment of Bacteriology-Virology-Parasitology, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.ORCID 0000-0002-9829-972X
Ovidiu Mircea ZlatianDepartment of Bacteriology-Virology-Parasitology, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.ORCID 0000-0003-3510-3838
Oana Mariana CristeaDepartment of Bacteriology-Virology-Parasitology, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.ORCID 0000-0003-0869-6738
Anca UngureanuDepartment of Bacteriology-Virology-Parasitology, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.
Radu Razvan MititeluDepartment of Bacteriology-Virology-Parasitology, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.ORCID 0000-0003-2998-689X
Andrei Theodor BalasoiuDepartment of Ophthalmology, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.
Corina Maria VasileDepartment of Paediatrics, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.ORCID 0000-0002-4684-8213
Alex-Ioan SalanDepartment of Oral and Maxillofacial Surgery, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.
Daniel IliutaDepartment of Psychiatry, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.
Mihaela PopescuDepartment of Endocrinology, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.
Anca-Loredana UdriștoiuFaculty of Automation, Computers and Electronics, University of Craiova, 200776 Craiova, Romania.ORCID 0000-0002-5560-6435
Maria BalasoiuDepartment of Bacteriology-Virology-Parasitology, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.
University of Medicine and Pharmacy of Craiova · ROUniversity of Craiova · RO

Funding

Incidence of Extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella strains and prediction of antibiotic resistance profiles using artificial intelligence algorithms" of University of Medicine and Pharmacy of Craiova, Romania 26/36/13.07
6 · The paper itself

Abstract

backgroundCTX-M betalactamases have shown a rapid spread in the recent years among Enterobacteriaceae and have become the most prevalent Extended Spectrum Beta-Lactamases (ESBLs) in many parts of the world. The introduction and dissemination of antibiotic-resistant genes limits options for treatment, increases mortality and morbidity in patients, and leads to longer hospitalization and expensive costs. We aimed to identify the beta-lactamases circulating encoded by the genes

methodsA total of 46 non-duplicated bacterial strains (14 strains of

results

conclusionsThe development in antibiotic resistance highlights the importance of establishing policies to reduce antibiotic use and improving the national resistance surveillance system in order to create local antibiotic therapy guidelines.

Indexed as

antibiotic resistanceantimicrobial resistanceCTX-M-15ESBLEscherichia coliKlebsiella pneumoniae

Identifiers

PMID35453254
PMCPMC9028254
OpenAlexW4223554839

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.