Evidence map›Paper›PMID 35453220›Full record

ReviewAntibiotics (Basel, Switzerland)2022

Phytocompounds as an Alternative Antimicrobial Approach in Aquaculture.

Naqiuddin Nik Mohamad Nek Rahimi, Ikhsan Natrah, Jiun-Yan Loh, Francis Kumar Ervin Ranzil, Madi Gina, Swee-Hua Erin Lim, Kok-Song Lai, Chou-Min Chong

Abstract readReview
In one paragraph

Review in Antibiotics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. In Vitro Screening of Butcher's Broom (Veterinary sciences · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Effects of Mangrove (Aquaculture nutrition · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Naqiuddin Nik Mohamad Nek RahimiAquatic Animal Health and Therapeutics Laboratory, Institute of Bioscience, University Putra Malaysia, Serdang 43400, Selangor, Malaysia.
Ikhsan NatrahAquatic Animal Health and Therapeutics Laboratory, Institute of Bioscience, University Putra Malaysia, Serdang 43400, Selangor, Malaysia.
Jiun-Yan LohCentre of Research for Advanced Aquaculture (CORAA), UCSI University, Cheras 56000, Kuala Lumpur, Malaysia.
Francis Kumar Ervin RanzilCentre of Research for Advanced Aquaculture (CORAA), UCSI University, Cheras 56000, Kuala Lumpur, Malaysia.
Madi GinaHealth Sciences Division, Abu Dhabi Women's College, Higher Colleges of Technology, Abu Dhabi 41012, United Arab Emirates.
Swee-Hua Erin LimHealth Sciences Division, Abu Dhabi Women's College, Higher Colleges of Technology, Abu Dhabi 41012, United Arab Emirates.ORCID 0000-0001-5177-0257
Kok-Song LaiHealth Sciences Division, Abu Dhabi Women's College, Higher Colleges of Technology, Abu Dhabi 41012, United Arab Emirates.
Chou-Min ChongAquatic Animal Health and Therapeutics Laboratory, Institute of Bioscience, University Putra Malaysia, Serdang 43400, Selangor, Malaysia.

Funding

Higher Colleges of Technology Interdisciplinary Research 97252Higher Institution Centre of Excellence (HICoE) 6369100Wellcome Trust 109055
6 · The paper itself

Abstract

Despite culturing the fastest-growing animal in animal husbandry, fish farmers are often adversely economically affected by pathogenic disease outbreaks across the world. Although there are available solutions such as the application of antibiotics to mitigate this phenomenon, the excessive and injudicious use of antibiotics has brought with it major concerns to the community at large, mainly due to the rapid development of resistant bacteria. At present, the use of natural compounds such as phytocompounds that can be an alternative to antibiotics is being explored to address the issue of antimicrobial resistance (AMR). These phytocompounds are bioactive agents that can be found in many species of plants and hold much potential. In this review, we will discuss phytocompounds extracted from plants that have been evidenced to contain antimicrobial, antifungal, antiviral and antiparasitic activities. Further, it has also been found that compounds such as terpenes, phenolics, saponins and alkaloids can be beneficial to the aquaculture industry when applied. This review will focus mainly on compounds that have been identified between 2000 and 2021. It is hoped this review will shed light on promising phytocompounds that can potentially and effectively mitigate AMR.

Indexed as

aquaculturechemical agentsherbal productsnatural remediesphytocompounds

Identifiers

PMID35453220
PMCPMC9031819

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.