Evidence map›Paper›PMID 35453200›Full record

ArticleAntibiotics (Basel, Switzerland)2022

Antibiotic Prescribing in Connection to Childbirth: An Observational Study in Two Districts in Lao PDR.

Weirong Yan, Anna Machowska, Amphoy Sihavong, Vanphanom Sychareun, Kongmany Chaleunvong, Bounxou Keohavong, Jaran Eriksen, Claudia Hanson, Manivanh Vongsouvath, Annelie Brauner and 3 more

Open access · goldAbstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 3 countries.

Weirong YanDepartment of Global Public Health, Karolinska Institutet, 171 77 Stockholm, Sweden.
Anna MachowskaDepartment of Global Public Health, Karolinska Institutet, 171 77 Stockholm, Sweden.
Amphoy SihavongVientiane Capital Health Department, Ministry of Health, Vientiane 01030, Laos.
Vanphanom SychareunFaculty of Public Health, University of Health Sciences (UHS), Vientiane 7444, Laos.
Kongmany ChaleunvongInstitute of Research and Education Development, UHS, Ministry of Health, Vientiane 01030, Laos.ORCID 0000-0002-9717-2946
Bounxou KeohavongFood and Drug Department, Ministry of Health, Vientiane 01030, Laos.
Jaran EriksenDepartment of Global Public Health, Karolinska Institutet, 171 77 Stockholm, Sweden.ORCID 0000-0003-1146-5615
Claudia HansonDepartment of Global Public Health, Karolinska Institutet, 171 77 Stockholm, Sweden.
Manivanh VongsouvathLao-Oxford-Mahosot Hospital-Welcome Trust Research Unit (LOMWRU), Microbiology Laboratory, Mahosot Hospital, Vientiane 01000, Laos.
Annelie BraunerDepartment of Microbiology, Tumor and Cell Biology, Karolinska Institutet, 171 77 Stockholm, Sweden.
Mayfong MayxayInstitute of Research and Education Development, UHS, Ministry of Health, Vientiane 01030, Laos.
Sengchanh KounnavongLao Tropical and Public Health Institute, Ministry of Health, Vientiane 01030, Laos.
Cecilia Stålsby LundborgDepartment of Global Public Health, Karolinska Institutet, 171 77 Stockholm, Sweden.ORCID 0000-0001-6525-1861
Karolinska Institutet · SEMinistry of Health · LAMahosot Hospital · LAKarolinska University Hospital · SEUniversity of Health Sciences Vientiane · LA

Funding

Karolinska Institutet internal funds grants 2018-01993, 2020-02146Southeast Asia Europe Joint Funding Scheme on Research and Innovation through Swedish Re-search Council 2018-01027
6 · The paper itself

Abstract

Overuse and misuse of antibiotics has frequently been reported for obstetric conditions and procedures, which may impact both the mother and the unborn baby and increase antibiotic resistance. This study aimed to investigate the antibiotic prescribing pattern in connection to childbirth in two districts in Lao PDR. It is a cross-sectional observational study. Antibiotic prescription data related to childbirth was collected via reviews of medical records in two district hospitals and five health centers in Lao PDR from September 2019 to November 2020. In total, antibiotic prescription data for 1777 women were extracted from their medical records. It was found that all women received antibiotics during in-patient care irrespective of delivery mode. When in hospital, 85.5% of the women who underwent a caesarean section got antibiotic treatment for 5 days and women who had a vaginal delivery usually had antibiotic treatment for one day or less. All the women got oral antibiotics for an additional 4-5 days upon discharge. Antibiotic prescription rate in connection to childbirth was very high in comparison with the WHO guidelines, and antibiotics were used extensively in the participating health facilities. Interventions to guide appropriate prescribing behavior in relation to childbirth are urgently needed in Lao PDR.

Indexed as

antibioticchildbirthLao PDRprescription

Identifiers

PMID35453200
PMCPMC9029038
OpenAlexW4220749494

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.