Evidence map›Paper›PMID 35453199›Full record

ArticleAntibiotics (Basel, Switzerland)2022

Comparative Analysis of the Antimicrobial Activity of Essential Oils and Their Formulated Microemulsions against Foodborne Pathogens and Spoilage Bacteria.

Raffaella Campana, Mattia Tiboni, Filippo Maggi, Loredana Cappellacci, Kevin Cianfaglione, Mohammad Reza Morshedloo, Emanuela Frangipani, Luca Casettari

Abstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Antibacterial, Synergistic, and Antibiofilm Activities ofAntibiotics (Basel, Switzerland) · 2026
    Article
  2. Review
  3. Food and waterborne parasitology · 2026
    Article
  4. In vitro characterization of probiotic properties of isolated and grown co-cultures on halophyte-based substrate.International microbiology : the official journal of the Spanish Society for Microbiology · 2026
    Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Effects ofFood science & nutrition · 2023
    Article
  12. Article
  13. Review
  14. Sea Fennel (Molecules (Basel, Switzerland) · 2023
    Review
  15. Chemical Composition of theAntibiotics (Basel, Switzerland) · 2023
    Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Raffaella CampanaDepartment of Biomolecular Sciences, University of Urbino, 61029 Urbino, Italy.ORCID 0000-0003-2196-4274
Mattia TiboniDepartment of Biomolecular Sciences, University of Urbino, 61029 Urbino, Italy.ORCID 0000-0002-3953-4937
Filippo MaggiSchool of Pharmacy, University of Camerino, 62032 Camerino, Italy.ORCID 0000-0003-1375-4744
Loredana CappellacciSchool of Pharmacy, University of Camerino, 62032 Camerino, Italy.ORCID 0000-0001-8155-7211
Kevin CianfaglioneUniversité de Lorraine, CNRS, LIEC, F-57000 Metz, France.ORCID 0000-0002-1336-1468
Mohammad Reza MorshedlooDepartment of Horticultural Science, Faculty of Agriculture, University of Maragheh, Maragheh 55136-553, Iran.ORCID 0000-0002-6028-3546
Emanuela FrangipaniDepartment of Biomolecular Sciences, University of Urbino, 61029 Urbino, Italy.ORCID 0000-0001-5619-7912
Luca CasettariDepartment of Biomolecular Sciences, University of Urbino, 61029 Urbino, Italy.ORCID 0000-0001-6907-8904

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The antimicrobial activity of several essential oils (EOs) and their related microemulsions (MEs) was investigated. EOs were obtained from Cannabis sativa L. cv CS (C. sativa), Carum carvi L. (C. carvi), Crithmum maritimum L. (C. maritimum), Cuminum cyminum L. (C. cyminum), x Cupressocyparis leylandii A.B. Jacks & Dallim. (C. leylandii), Cupressus arizonica Greene (C. arizonica), Ferula assa-foetida L. (F. assa-foetida)., Ferula gummosa Boiss. (F. gummosa), Juniperus communis L. (J. communis), Juniperus x pfitzeriana (Spath) P.A. Schmidt (J. pfitzeriana), Pimpinella anisum L (P. anisum). Preliminary screening revealed that Cuminum cyminum, Crithmum maritimum, and Pimpinella anisum (10% v/v) were effective against all tested microorganisms (Escherichia coli ATCC 35218, Listeria monocytogenes ATCC 7644, Staphylococcus aureus ATCC 29213, Pseudomonas fluorescens DSM 4358, and Candida albicans ATCC 10231), with growth inhibition diameter from 10 to 25 mm. These EOs were used to formulate the MEs with an average size < 50 nm and a good stability over 30 days. EOs’ antimicrobial activity was further enhanced in the MEs, with a generalized lowering of minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) values. C. cyminum-ME reached, in most cases, MIC two times lower (0.312%) than the corresponding EO (0.625%) and even eight times lower against S. aureus (0.156 vs. 1.25%). A more remarkable microbicide effect was noted for C. cyminum-ME, with MBC values eight times lower (from 0.312 to 0.625%) than the corresponding EO (from 2.5 to 5%). Overall, MEs resulted in an efficient system for EOs encapsulation, enhancing solubility and lowering concentration to exert antimicrobial efficacy.

Indexed as

antimicrobial efficacydynamic light scatteringessential oilsmicroemulsionpathogens

Identifiers

PMID35453199
PMCPMC9025571

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.