Evidence map›Paper›PMID 35453169›Full record

ArticleEuropean journal of dentistry2023

Anti-Periodontopathogenic Ability of Mangrove Leaves (Aegiceras corniculatum) Ethanol Extract: In silico and in vitro study.

Alexander Patera Nugraha, Mada Triandala Sibero, Albertus Putera Nugraha, Martining Shoffa Puspitaningrum, Yuniar Rizqianti, Desintya Rahmadhani, Viol Dhea Kharisma, Nastiti Faradilla Ramadhani, Rini Devijanti Ridwan, Tengku Natasha Eleena Binti Tengku Ahmad Noor and 1 more

Open access · hybridAbstract read
In one paragraph

Article in European journal of dentistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Emerging strategies for combatingExploration (Beijing, China) · 2024
    Review
  6. Article
  7. Phytochemical, antioxidant, and antibacterial activity ofJournal of oral biology and craniofacial research
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Alexander Patera NugrahaDepartment Orthodontics, Faculty of Dental Medicine, Universitas Airlangga, Surabaya, Indonesia.
Mada Triandala SiberoMarine Science Department, Faculty of Fisheries and Marine Science, Diponegoro University, Semarang, Indonesia.ORCID 0000-0001-5832-4399
Albertus Putera NugrahaFaculty of Medicine, Universitas Airlangga, Universitas Airlangga, Surabaya, Indonesia.
Martining Shoffa PuspitaningrumFaculty of Dental Medicine, Universitas Airlangga, Universitas Airlangga, Surabaya, Indonesia.
Yuniar RizqiantiFaculty of Dental Medicine, Universitas Airlangga, Universitas Airlangga, Surabaya, Indonesia.
Desintya RahmadhaniFaculty of Dental Medicine, Universitas Airlangga, Universitas Airlangga, Surabaya, Indonesia.
Viol Dhea KharismaDepartment of Biology, Faculty of Mathematic and Natural Science, Universitas Brawijaya, Surabaya, Indonesia.
Nastiti Faradilla RamadhaniDentomaxillofacial Department, Faculty of Dental Medicine, Universitas Airlangga, Surabaya, Indonesia.
Rini Devijanti RidwanDepartment of Oral Biology, Faculty of Dental Medicine, Universitas Airlangga, Surabaya, Indonesia.
Tengku Natasha Eleena Binti Tengku Ahmad Noor609 Armed Forces Dental Clinic, Kem Semenggo, Kuching, Sarawak, Malaysia.
Diah Savitri ErnawatiDepartment of Oral Medicine, Faculty of Dental Medicine, Universitas Airlangga, Surabaya, Indonesia.
Airlangga University · IDDiponegoro University · IDSarawak General Hospital · MYUniversity of Brawijaya · ID

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveMangrove ( MATERIALS AND

methodsPhytochemistry and liquid chromatography-high resolution mass spectrometry (LC-HRMS) were done to explore the active compounds in MLE. Chemistry screening and interaction, absorption, distribution, metabolism, and excretion (ADME), molecular docking simulation, and visualization of MLE active compounds as anti-inflammatory, antioxidant, and antibacterial were investigated

resultsAlkaloid, saponin, flavonoid, triterpenoid, steroid, tannin, and quinone were detected in MLE. A high concentration of (-)epicatechin and coumaric acid (CA) were found in MLE. MLE in 100% concentration has the most effective ability to inhibit

conclusionMLE of

Identifiers

PMID35453169
PMCPMC9949921
OpenAlexW4224225923

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.