Evidence map›Paper›PMID 35452755›Full record

ArticleJournal of affective disorders2022

Prevalence of stressful life events and associations with symptoms of depression, anxiety, and post-traumatic stress disorder among people entering care for HIV in Cameroon.

Lindsey M Filiatreau, Peter Vanes Ebasone, Anastase Dzudie, Rogers Ajeh, Brian W Pence, Milton Wainberg, Denis Nash, Marcel Yotebieng, Kathryn Anastos, Eric Pefura-Yone and 2 more

Open access · greenAbstract read
In one paragraph

Article in Journal of affective disorders, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.7field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 2 countries.

Lindsey M FiliatreauWashington University in St. Louis, School of Medicine, Department of Psychiatry, St. Louis, MO, United States of America; Washington University in St. Louis, Brown School, International Center for Child Health and Development, St. Louis, MO, United States of America; University of North Carolina at Chapel Hill, Carolina Population Center, Chapel Hill, NC, United States of America. Electronic address: flindsey@wustl.edu.
Peter Vanes EbasoneClinical Research Education Networking and Consultancy, Yaounde, Cameroon.
Anastase DzudieClinical Research Education Networking and Consultancy, Yaounde, Cameroon.
Rogers AjehClinical Research Education Networking and Consultancy, Yaounde, Cameroon.
Brian W PenceUniversity of North Carolina at Chapel Hill, Gillings School of Global Public Health, Department of Epidemiology, Chapel Hill, NC, United States of America.
Milton WainbergColumbia University, Department of Psychiatry, New York, NY, United States of America.
Denis NashCity University of New York, Institute of Implementation Science in Population Health, New York, NY, United States of America.
Marcel YotebiengAlbert Einstein College of Medicine, Department of Medicine, Bronx, NY, United States of America.
Kathryn AnastosAlbert Einstein College of Medicine, Department of Medicine, Bronx, NY, United States of America; Albert Einstein College of Medicine, Department of Epidemiology & Population Health, Bronx, NY, United States of America.
Eric Pefura-YoneJamot Hospital, Yaounde, Cameroon.
Denis NsameBamenda Regional Hospital, Bamenda, Cameroon.
Angela M ParcesepeUniversity of North Carolina at Chapel Hill, Carolina Population Center, Chapel Hill, NC, United States of America; University of North Carolina at Chapel Hill, Gillings School of Global Public Health, Department of Maternal and Child Health, Chapel Hill, NC, United States of America.
University of North Carolina at Chapel Hill · USAlbert Einstein College of Medicine · USBamenda University of Science and Technology · CMCity University of New York · USColumbia University · USYaoundé General Hospital · CM

Funding

Virology, Immunology, and Microbiology CoreP30AI050410 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DAVID M. MARGOLIS · 2001 to 2026
$76.9M
"Enhancing Cancer Research in Central Africa IeDEA"U01AI096299 · NIAID · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI Denis Nash, Marcel Yotebieng · 2011 to 2026
$35.8M
Carolina Population CenterR24HD050924 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI MORGAN, SAMUEL PHILIP · 2005 to 2014
$10.0M
Research Services CoreP2CHD050924 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI KAREN B GUZZO · 2015 to 2026
$9.6M
Training LEADers to Accelerate Global Mental Health Disparities in Research (LEAD)T37MD014218 · NIMHD · WASHINGTON UNIVERSITY · PI CAVAZOS-REHG, PATRICIA A, SSEWAMALA, FRED M · 2019 to 2023
$1.3M
Understanding and addressing mental and substance use disorders among people living with HIV in low-resource settingsK01MH114721 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI PARCESEPE, ANGELA · 2018 to 2022
$766k
NIAID NIH HHS P30 AI050410NIAID NIH HHS U01 AI096299NICHD NIH HHS P2C HD050924NICHD NIH HHS R24 HD050924NIMHD NIH HHS T37 MD014218NIMH NIH HHS K01 MH114721
6 · The paper itself

Abstract

backgroundExposure to stressors increases the risk of mental health disorders. People living with HIV (PLWH) are particularly affected by poor mental health which can contribute to adverse HIV treatment outcomes.

methodsWe estimated the prevalence of recent stressful life events (modified Life Events Survey) among a cohort of PLWH entering HIV care at three public health care facilities in Cameroon and quantified the association of seven types of stressful life events with symptoms of depression (Patient Health Questionnaire-9 scores>9), anxiety (General Anxiety Disorder-7 scores>9), and PTSD (PTSD Checklist for DSM-5 scores>30) using separate log-binomial regression models.

resultsOf 426 PLWH enrolling in care, a majority were women (59%), in relationships (58%), and aged 21 to 39 years (58%). Recent death of a family member (39%) and severe illness of a family member (34%) were the most commonly reported stressful life events. In multivariable analyses, more stressful life event types, a negative relationship change, death or illness of a friend/family member, experience of violence, work-related difficulties, and feeling unsafe in one's neighborhood were independently associated with at least one of the mental health outcomes assessed. The greatest magnitude of association was observed between work-related difficulties and PTSD (adjusted prevalence ratio: 3.1; 95% confidence interval: 2.0-4.8). LIMITATIONS: Given the design of our study, findings are subject to recall and social desirability bias.

conclusionsStressful life events were common among this population of PLWH entering care in Cameroon. Evidence-based interventions that improve coping, stress management, and mental health are needed.

Indexed as

HIV InfectionsStress Disorders, Post-TraumaticAnxietyAnxiety DisordersCameroonDepressionFemaleHumansMalePrevalenceAnxietyCameroonDepressionHIVPTSDStressful life events

Identifiers

PMID35452755
PMCPMC9520993
OpenAlexW4224286456

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.