Evidence map›Paper›PMID 35452552›Full record

ReviewAmerican journal of reproductive immunology (New York, N.Y. : 1989)2022

COVID-19 disease and vaccination in pregnant and lactating women.

Marco A P Safadi, Julia Spinardi, David Swerdlow, Amit Srivastava

Open access · hybridAbstract readReview
In one paragraph

Review in American journal of reproductive immunology (New York, N.Y. : 1989), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Monoclonal Antibody Therapy of Breastfeeding Patient Infected with SARS-CoV-2: A Case Report.Breastfeeding medicine : the official journal of the Academy of Breastfeeding Medicine · 2023
    Article
  6. Article
  7. An Update on COVID-19 Vaccination and Pregnancy.Journal of personalized medicine · 2023
    Review
  8. Article
  9. Article
  10. COVID-19 Vaccines and the Virus: Impact on Drug Metabolism and Pharmacokinetics.Drug metabolism and disposition: the biological fate of chemicals · 2023
    Review
  11. Article
  12. COVID-19 disease and vaccination in pregnant and lactating women.American journal of reproductive immunology (New York, N.Y. : 1989) · 2022
    Review
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Marco A P SafadiDepartment of Pediatrics, Santa Casa de Sao Paulo School of Medical Sciences, Sao Paulo, Brazil.
Julia SpinardiVaccine Medical Affairs - Emerging Markets, Pfizer Inc, Sao Paulo, Brazil.
David SwerdlowPfizer Vaccines, Collegeville, Pennsylvania, USA.
Amit SrivastavaVaccines, Medical Development, Scientific and Clinical Affairs, Pfizer Inc, Cambridge, Massachusetts, USA.ORCID 0000-0002-2510-5058
Pfizer (United States) · USFaculdade de Ciências Médicas da Santa Casa de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMore than 325,000 cases of coronavirus disease 2019 (COVID-19) have been reported among pregnant women in the Americas.

aimsThis review examines the impact of COVID-19 in pregnant women and describes available evidence on the safety, effectiveness, and immune response(s) to vaccination among pregnant and lactating women. CONTENT: Multiple studies indicate that pregnant women are more susceptible to adverse COVID-19 outcomes, including hospitalization, intensive care unit admission, and invasive ventilation than non-pregnant women with COVID-19. Furthermore, COVID-19 in pregnancy is associated with adverse maternal and neonatal outcomes. Adverse COVID-19 outcomes appear to disproportionately affect pregnant women from low- and middle-income countries, likely reflecting inequities in access to quality healthcare. Despite the absence of safety and efficacy data from randomized clinical trials in this subpopulation, observational studies and data from pregnancy registries thus far have demonstrated that vaccination of pregnant or lactating women against COVID-19 is safe, effective, and results in robust immune responses including transfer of antibodies to the newborn via the placenta and breast milk, respectively. IMPLICATIONS: These data support vaccination recommendations intending to help protect these vulnerable individuals against COVID-19 and its sequelae. Randomized clinical studies will further evaluate the safety and immunogenicity of COVID-19 vaccines in these populations. This review examines the impact of COVID-19 in pregnant women and describes available evidence on the safety, effectiveness, and immune response(s) to vaccination among pregnant and lactating women.

Indexed as

COVID-19COVID-19 VaccinesFemaleHospitalizationHumansInfant, NewbornLactationPregnancyVaccinationCOVID-19 VaccinesCOVID-19COVID-19 vaccinesimmunogenicitylactationpregnancysafetySARS-CoV-2VACCINATION

Identifiers

PMID35452552
PMCPMC9111214
OpenAlexW4224272803

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.