Evidence map›Paper›PMID 35452383›Full record

ReviewEmerging infectious diseases2022

Detection of SARS-CoV-2 B.1.351 (Beta) Variant through Wastewater Surveillance before Case Detection in a Community, Oregon, USA.

Melissa Sutton, Tyler S Radniecki, Devrim Kaya, Dana Alegre, Matthew Geniza, Anne-Marie Girard, Katherine Carter, Mark Dasenko, Justin L Sanders, Paul R Cieslak and 2 more

Open access · diamondAbstract readReview
In one paragraph

Review in Emerging infectious diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 42 citations in OpenAlex.

  1. Article
  2. Wastewater Metagenomic Virome Analysis of the 2026 World Cup in Texas.medRxiv : the preprint server for health sciences · 2026
    Article
  3. Article
  4. Review
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  6. Article
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  9. Outbreak-associatedJournal of clinical microbiology · 2024
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Structured Ethical Review for Wastewater-Based Testing.medRxiv : the preprint server for health sciences · 2023
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Melissa Sutton
Tyler S Radniecki
Devrim Kaya
Dana Alegre
Matthew Geniza
Anne-Marie Girard
Katherine Carter
Mark Dasenko
Justin L Sanders
Paul R Cieslak
Christine Kelly
Brett M Tyler
Oregon Health Authority · USOregon State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Genomic surveillance has emerged as a critical monitoring tool during the SARS-CoV-2 pandemic. Wastewater surveillance has the potential to identify and track SARS-CoV-2 variants in the community, including emerging variants. We demonstrate the novel use of multilocus sequence typing to identify SARS-CoV-2 variants in wastewater. Using this technique, we observed the emergence of the B.1.351 (Beta) variant in Linn County, Oregon, USA, in wastewater 12 days before this variant was identified in individual clinical specimens. During the study period, we identified 42 B.1.351 clinical specimens that clustered into 3 phylogenetic clades. Eighteen of the 19 clinical specimens and all wastewater B.1.351 specimens from Linn County clustered into clade 1. Our results provide further evidence of the reliability of wastewater surveillance to report localized SARS-CoV-2 sequence information.

Indexed as

COVID-19SARS-CoV-2HumansOregonPhylogenyReproducibility of ResultsWastewaterWastewater-Based Epidemiological MonitoringWastewatercoronavirus diseaseCOVID-19genomic epidemiologyMLSTmultilocus sequence typingnext-generation sequencingNGSOregonpublic healthrespiratory infectionsSARS-CoV-2severe acute respiratory syndrome coronavirus 2vaccine-preventable diseasesviruseswastewater-based epidemiologywastewater surveillancezoonoses

Identifiers

PMID35452383
PMCPMC9155900
OpenAlexW4224312967

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.