ArticleThe Medical journal of Australia2022
Cholecystectomy for people aged 50 years or more with mild gallstone pancreatitis: predictors and outcomes of index and interval procedures.
Article in The Medical journal of Australia, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 7 citations in OpenAlex.
- Article
- MANagement of Gallstone disease in the Older patient (MANGO): clinical and quality of life outcomes from a prospective multicentre cohort study.BMC surgery · 2026Observational
- National Trends in Interventions for Pediatric Gallstone Pancreatitis.Journal of laparoendoscopic & advanced surgical techniques. Part A · 2024Article
- Time to interval cholecystectomy and associated outcomes in a population aged 50 and above with mild gallstone pancreatitis.Langenbeck's archives of surgery · 2023Article
- External application of mirabilite before surgery can reduce the inflammatory response and accelerate recovery in mild acute biliary pancreatitis.BMC gastroenterology · 2023Article
- Clearing elective surgery waiting lists after the COVID-19 pandemic cannot be allowed to compromise emergency surgery care.The Medical journal of Australia · 2022Article
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Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo estimate the proportions of people aged 50 years or more with mild gallstone pancreatitis who undergo index cholecystectomy (during their initial hospital admission) or interval cholecystectomy (during a subsequent admission); to compare outcomes following index and interval cholecystectomy; and to identify factors associated with undergoing interval cholecystectomy. DESIGN, SETTING,
participantsAnalysis of linked hospitalisation and deaths data for all people aged 50 years or more with mild gallstone pancreatitis who underwent cholecystectomy in New South Wales within twelve months of their index admission, 1 July 2008 - 30 June 2018.
main outcome measuresCholecystectomy classification (index or interval). SECONDARY OUTCOMES: all-cause mortality (30-365 days), emergency re-admissions with gallstone-related disease (within 28 or 180 days of discharge); hospital lengths of stay (index admission, and all admissions with gallstone-related disease over six months).
resultsA total of 1836 patients underwent index cholecystectomy (37.9%) and 3003 interval cholecystectomy (62.1%). Mortality to twelve months was similar in the two groups. Larger proportions of people who underwent interval cholecystectomy were re-admitted within 28 days (246, 8.2% v 23, 1.3%) or 180 days (527, 17.6% v 59, 3.2%), or required open cholecystectomy (238, 7.9% v 69, 3.8%). Mean index admission length of stay was longer for index than interval cholecystectomy (7.7 [SD, 4.7] days v 5.3 [SD, 3.9] days), but six-month total length of stay was similar (8.2 [SD, 5.6] days v 7.9 [SD, 5.8] days). Interval cholecystectomy was more likely for patients with three or more comorbid conditions (adjusted odds ratio [aOR], 1.29; 95% CI, 1.08-1.55) or private health insurance (aOR, 1.31; 95% CI, 1.13-1.51), and for those admitted to low surgical volume hospitals (aOR, 1.84; 95% CI, 1.03-3.31).
conclusionsMost NSW people over 50 with mild gallstone pancreatitis did not undergo index cholecystectomy, despite recommendations in international guidelines. Delayed cholecystectomy was associated with more frequent open cholecystectomy procedures and gallstone disease-related emergency re-admissions, as well as with low or medium hospital surgical volume, comorbidity, and having private insurance.
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