ArticleJMIR cancer2022
Barriers to Clinical Trial Participation: Comparative Study Between Rural and Urban Participants.
Article in JMIR cancer, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 35 citations in OpenAlex.
- Recruiting Rural Patients for Clinical Research: Lessons From a Colorectal Cancer Screening Trial.The Journal of rural health : official journal of the American Rural Health Association and the National Rural Health Care Association · 2026Trial
- Exploring Racial Disparities in Awareness and Perceptions of Oncology Clinical Trials: Cross-Sectional Analysis of Baseline Data From the mychoice Study.JMIR cancer · 2024Trial
- Development and initial validation of a scale assessing sources of decision hesitation in patients with lung cancer invited to participate in drug clinical trials.Asia-Pacific journal of oncology nursing · 2026Article
- Understanding Cancer Clinical Trial Participation in Rural Communities: A Qualitative Focus Group Study.Psycho-oncology · 2026Article
- Cancer clinical trial recruitment for patients from rural areas: a scoping review.International journal for equity in health · 2026Article
- A Geographic Disparities Analysis Between Standard of Care and Clinical Trial CAR-T Patients in Kansas.Cancer medicine · 2026Article
- Preferred conditions for promoting participation in on-site oral health surveys among Japanese adults: insights from a conjoint analysis.BMC public health · 2026Article
- Disparities in Psychosocial Outcomes Among Pediatric Cancer Survivors Living in Rural and Appalachian Areas.Pediatric blood & cancer · 2026Article
- Perceptions of health research participation in rural and urban Pennsylvanians.Journal of clinical and translational science · 2026Article
- Bridging the gap: Community insights on effectively sharing research findings with the public.Journal of clinical and translational science · 2026Article
- Bridging the rural cancer gap: why clinical trials must include rural patients.Cancer causes & control : CCC · 2025Article
- Potential Barriers to Participating in Cancer Moonshot Biobank for Low-Income Patients with Cancer of Rural Maine.Biopreservation and biobanking · 2025Article
- Exclusion of people from oncology clinical trials based on functional status.Clinical trials (London, England) · 2025Article
- Addressing challenges and barriers to rural Veteran participation in clinical research within the Veterans Affairs healthcare system.Contemporary clinical trials communications · 2025Article
- 'The seagull theory: Where people fly in, gather information… fly out and nothing ever comes about': A qualitative exploration of barriers and enablers to research participation among adults with type 2 diabetes living in Australian rural communities.Diabetic medicine : a journal of the British Diabetic Association · 2025Article
- Therapeutic Clinical Trial Eligibility and Enrollment among Women with Breast Cancer: Implications for Understanding Trial Disparities.Annals of surgical oncology · 2025Article
- Development of clinical research networks in rural America: Our experience from the Accelerating COVID-19 Therapeutic Interventions and Vaccines-1 trialau.Journal of clinical and translational science · 2025Article
- Barriers to participation in clinical trials of rural older adult cancer survivors: A qualitative study.The Journal of rural health : official journal of the American Rural Health Association and the National Rural Health Care Association · 2025Article
- Barriers and facilitators to recruitment of rural patients to cancer clinical trials.Proceedings (Baylor University. Medical Center) · 2025Review
- Screening log: Challenges in community patient recruitment for gynecologic oncology clinical trials.Contemporary clinical trials communications · 2024Article
Corrections and comments
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
Abstract
backgroundThe National Clinical Trials Network program conducts phase 2 or phase 3 treatment trials across all National Cancer Institute's designated cancer centers. Participant accrual across these clinical trials is a critical factor in deciding their success. Cancer centers that cater to rural populations, such as The University of Kansas Cancer Center, have an additional responsibility to ensure rural residents have access and are well represented across these studies.
objectiveThere are scant data available regarding the factors that act as barriers to the accrual of rural residents in these clinical trials. This study aims to use electronic screening logs that were used to gather patient data at several participating sites in The Kansas University of Cancer Center's Catchment area.
methodsScreening log data were used to assess what clinical trial participation barriers are faced by these patients. Additionally, the differences in clinical trial participation barriers were compared between rural and urban participating sites.
resultsAnalysis revealed that the hospital location rural urban category, defined as whether the hospital was in an urban or rural setting, had a medium effect on enrolment of patients in breast cancer and lung cancer trials (Cohen d=0.7). Additionally, the hospital location category had a medium effect on the proportion of recurrent lung cancer cases at the time of screening (d=0.6).
conclusionsIn consideration of the financially hostile nature of cancer treatment as well as geographical and transportation barriers, clinical trials extended to rural communities are uniquely positioned to alleviate the burden of nonmedical costs in trial participation. However, these options can be far less feasible for patients in rural settings. Since the number of patients with cancer who are eligible for a clinical trial is already limited by the stringent eligibility criteria required of such a complex disease, improving accessibility for rural patients should be a greater focus in health policy.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.