Evidence map›Paper›PMID 35451960›Full record

ArticleeLife2022

Widespread nociceptive maps in the human neonatal somatosensory cortex.

Laura Jones, Madeleine Verriotis, Robert J Cooper, Maria Pureza Laudiano-Dray, Mohammed Rupawala, Judith Meek, Lorenzo Fabrizi, Maria Fitzgerald

Open access · goldAbstract read
In one paragraph

Article in eLife, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. The fetal pain paradox.Frontiers in pain research (Lausanne, Switzerland) · 2023
    Review
  6. Early Life Pain Experience Changes Adult Functional Pain Connectivity in the Rat Somatosensory and the Medial Prefrontal Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022
    Article
  7. Article
  8. Article
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Laura JonesDepartment of Neuroscience, Physiology & Pharmacology, University College London, London, United Kingdom.ORCID 0000-0001-5755-4977
Madeleine VerriotisDepartment of Neuroscience, Physiology & Pharmacology, University College London, London, United Kingdom.ORCID 0000-0003-3019-0370
Robert J CooperDepartment of Developmental Neuroscience, University College London, London, United Kingdom.
Maria Pureza Laudiano-DrayDepartment of Neuroscience, Physiology & Pharmacology, University College London, London, United Kingdom.
Mohammed RupawalaDepartment of Neuroscience, Physiology & Pharmacology, University College London, London, United Kingdom.
Judith MeekElizabeth Garrett Anderson Obstetric Wing, University College London Hospitals, London, United Kingdom.
Lorenzo FabriziDepartment of Neuroscience, Physiology & Pharmacology, University College London, London, United Kingdom.ORCID 0000-0002-9582-0727
Maria FitzgeraldDepartment of Neuroscience, Physiology & Pharmacology, University College London, London, United Kingdom.ORCID 0000-0003-4188-0123
University College London · GBUniversity College Hospital · GB

Funding

Medical Research Council MR/L019248/1Medical Research Council MR/M006468/1Medical Research Council MR/S003207/1
6 · The paper itself

Abstract

Topographic cortical maps are essential for spatial localisation of sensory stimulation and generation of appropriate task-related motor responses. Somatosensation and nociception are finely mapped and aligned in the adult somatosensory (S1) cortex, but in infancy, when pain behaviour is disorganised and poorly directed, nociceptive maps may be less refined. We compared the topographic pattern of S1 activation following noxious (clinically required heel lance) and innocuous (touch) mechanical stimulation of the same skin region in newborn infants (

Indexed as

NociceptionSomatosensory CortexAdultBrain MappingHumansInfantInfant, NewbornPainTouchbraindevelopmenthumaninfantneurosciencepainsomatotopytopography

Identifiers

PMID35451960
PMCPMC9090328
OpenAlexW4225553626

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.