ReviewThe British journal of radiology2022
Multidelay ASL of the pediatric brain.
Review in The British journal of radiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Meta-analysis of arterial spin labeling MRI to identify residual cerebral arteriovenous malformations after treatment.BMC medical imaging · 2025Pooled it
- Advanced MRI methods for children and young adults with autosomal recessive polycystic kidney disease (ARPKD) to support future multi-center clinical trials.Pediatric radiology · 2026Review
- Clinical utility of Arterial Spin Labeling perfusion images in pediatric neurological emergencies.La Radiologia medica · 2026Review
- Visualizing pain-processing networks with 7T resting-state functional MRI using pseudo-continuous arterial spin labeling.Scientific reports · 2026Article
- Neurovascular coupling dysfunction of the frontal‒thalamic circuit in postconcussion syndrome.Brain imaging and behavior · 2026Article
- Association of dynamic changes in ASPECTS perfusion scores derived from dual-time-point multi-post-labeling delay arterial spin labeling with 90-day functional outcome in acute ischemic stroke.American journal of translational research · 2026Article
- Age-related changes in cerebral blood flow and arterial transit time in children: insights from single- and multi-delay ASL.Neuroradiology · 2025Article
- ISMRM Clinical Focus Meeting 2023: "Imaging the Fire in the Brain".Journal of magnetic resonance imaging : JMRI · 2025Article
- Cerebral hemodynamics evaluation of FLAIR vascular hyperintensity in TIA patients with large artery severe stenosis or occlusion.Frontiers in neurology · 2025Article
- Altered cerebral perfusion in Parkinson's disease patients with anxiety: an arterial spin labeling MRI study.Frontiers in neurology · 2025Article
- Comparison of SPECT/CT, AEEG, and 3D-pCASL in people with epilepsy.Frontiers in neurology · 2025Article
- Comparison of normalized cerebral blood flow between different post-processing methods of dynamic susceptibility contrast perfusion-weighted imaging and arterial spin labeling in gliomas with different grading.Quantitative imaging in medicine and surgery · 2024Article
- Transformer-based deep learning denoising of single and multi-delay 3D arterial spin labeling.Magnetic resonance in medicine · 2024Article
- Prognostic value of multi-PLD ASL radiomics in acute ischemic stroke.Frontiers in neurology · 2024Article
- Prognostic value of multi-PLD ASL-based cerebral perfusion ASPECTS in acute ischemic stroke.Frontiers in neurology · 2024Article
- Assessment of brainstem function and haemodynamics by MRI: challenges and clinical prospects.The British journal of radiology · 2023Review
- Arterial spin labeling MRI applied to migraine: current insights and future perspectives.The journal of headache and pain · 2023Review
- Advanced Neuromonitoring Modalities on the Horizon: Detection and Management of Acute Brain Injury in Children.Neurocritical care · 2023Review
- Three-dimensional pseudocontinuous arterial spin labeling perfusion imaging shows cerebral blood flow perfusion decline in attention-deficit/hyperactivity disorder children.Frontiers in psychiatry · 2023Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
Arterial spin labeling (ASL) is a powerful noncontrast MRI technique for evaluation of cerebral blood flow (CBF). A key parameter in single-delay ASL is the choice of postlabel delay (PLD), which refers to the timing between the labeling of arterial free water and measurement of flow into the brain. Multidelay ASL (MDASL) utilizes several PLDs to improve the accuracy of CBF calculations using arterial transit time (ATT) correction. This approach is particularly helpful in situations where ATT is unknown, including young subjects and slow-flow conditions. In this article, we discuss the technical considerations for MDASL, including labeling techniques, quantitative metrics, and technical artefacts. We then provide a practical summary of key clinical applications with real-life imaging examples in the pediatric brain, including stroke, vasculopathy, hypoxic-ischemic injury, epilepsy, migraine, tumor, infection, and metabolic disease.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.